Results 81 to 90 of about 46,262,713 (232)
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Securitas Mare - Crowd and Crisis Management [PDF]
TransNav, 2007 Shipping is by nature a genuinely international activity, with strict requirements for harmonized and equal training, regardless of where it is conducted. IMO?s model courses aims to give guidance in this respect. However, each signatory party to STCW-95
Christer Bergquist
doaj
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Safety Control of Maritime Traffic Near by Offshore in Time [PDF]
TransNav, 2011 This paper introduces and presents a strategy for ensuring safety during control of vessel interaction in real time. A measure of danger during the interaction is explicitly computed, based on factors affecting the impact force during a potential ...
Daegwun Yoon +4 more
doaj
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
OSU/Sea Grant Extension Tourism, and Outdoor Recreation Program [PDF]
What are OSU Extension and Sea ...
Phillips, Miles
core +3 more sources
The MarEng Project - a Tool for Enhancing Safety in Navigation and Maritime Transport [PDF]
TransNav, 2007 In the paper the MarEng project is presented as a tool for enhancing safety in navigation and maritime transport.
Barbara Katarzynska
doaj
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Confluence : Spring/Summer 2018 - print version
Confluence is a newsletter of Oregon Sea Grant.
Oregon State University. Sea Grant College Program
core +3 more sources
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source