Results 31 to 40 of about 468,294 (264)
Journal of Community Hospital Internal Medicine Perspectives, 2020 Background Patient safety events (PSE) are opportunities to improve patient care but physicians rarely report them. In a previous study, residents identified knowledge regarding what constitutes a PSE, perceived lack of time, complexity of the reporting ...
Mukul Singal +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Safety and Health Perceptions in Work-related Transport Activities in Ghanaian Industries
Safety and Health at Work, 2017 Background: With the recent rapid industrialization, occupational safety and health (OSH) has become an important issue in all industrial and human activities.
Charles Atombo +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
SWISS CHEESE IN BRAZIL: DISASTER CULTURE AND SAFETY CULTURE IN DISASTERS [PDF]
Ambiente & SociedadeThis article discusses points related to “disaster culture” and “safety culture” in Brazil, and debates how societal-structural factors influence the management of low incidence and high consequence disasters, such as dam breaks, which appear to provide ...
JEROEN WARNER +2 more
doaj +4 more sources
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Leadership Style and Safety Culture in Commuter Railroads
SafetyPrevious research has repeatedly demonstrated the importance of both safety culture and leadership in promoting workplace safety. Several studies and reviews have identified transformational leadership style as an important contributor to a strong safety
Patrick Sherry
doaj +1 more source
Evaluation of Safety Culture among Healthcare Workers in Borujerd [PDF]
Muhandisī-i bihdāsht-i ḥirfah/ī, 2023 Background and Objective: A proper safety culture is one of the important factors that ensure a healthy and safe work environment. In order to ensure safety performance in the workplace, healthcare departments are required to establish safety rules and ...
Hamed Ahmadpour +3 more
doaj
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source