Results 41 to 50 of about 491,649 (265)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Health in Emergencies & Disasters Quarterly, 2022 Background: Safety plays a significant role in the oil & gas industries, where there are many risk factors that can cause accidents. This study aims to evaluate the level of safety culture among the employees of the operational units of South Zagros Oil &
Mohammad Reza Omidi +2 more
doaj
Evaluation of Safety Culture among Healthcare Workers in Borujerd [PDF]
Muhandisī-i bihdāsht-i ḥirfah/ī, 2023 Background and Objective: A proper safety culture is one of the important factors that ensure a healthy and safe work environment. In order to ensure safety performance in the workplace, healthcare departments are required to establish safety rules and ...
Hamed Ahmadpour +3 more
doaj
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Applied SciencesThe electric power industry, as a High-Reliability Organization (HRO), demands a mature safety culture. However, existing diagnostic tools often lack industry specificity.
Sangwook Han +4 more
doaj +1 more source
The safety culture stack – the next evolution of safety culture? [PDF]
Safety and Reliability, 2018 Since its inception following the Chernobyl nuclear power plant disaster in 1986, safety culture has impacted a number of industries, including nuclear power, the oil and gas industry, rail, health...
Barry Kirwan, Tom Reader, Anam Parand
openaire +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Risk Management and Healthcare Policy, 2022 Xiaoying Zhao,1 Chunhong Shi,2,3 Lihua Zhao1 1Handan First Hospital, Handan, 056000, People’s Republic of China; 2School of Nursing, Xiangnan University, Chenzhou, People’s Republic of China; 3Affiliated Hospital of Xiangnan University, Chenzhou, 423000,
Zhao X, Shi C, Zhao L
doaj
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source