Results 131 to 140 of about 19,469,886 (406)

79P A prospective, single-arm, phase II study to evaluate the efficacy and safety of tislelizumab plus chemotherapy in resectable NSCLC [PDF]

, 2023
Dalin Sun, M. Wang
openalex   +1 more source

Evaluation of safety of Azdirachta indica seed oil on Albino rat through haematological and some antioxidants by the rotatable central composite design (RCCD) of the response surface methodology (RSM) [PDF]

, 2018
Raw Azdirachta indica seed oil is gradually adopted by local farmers as a protector of stored grains and legumes against the common insects, but with some reservations on its safety. The study investigated the safety A.
G, U. P. (Udofia), Phillippa, O. (Ojimelukwe), Ukom, A. (Anthony)   +2 more
core  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Postpartum Safety and Satisfaction Following Early Discharge [PDF]

, 1996
Two Ontario sites were involved in the evaluation of an obstetrical discharge program. Before program implementation a group of eligible women were enrolled as the preprogram control group (n = 542). During the program, eligible women who agreed to early
Guthrie, Dawn M., Hodnett, Ellen, Rush, Janet, Williams, J. Ivan   +3 more
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

The crystal structure of methyl 4-(4-(methylsulfonyl)phenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, C19H21NO5S

Zeitschrift für Kristallographie - New Crystal Structures
C19H21NO5S, triclinic, P1̄ (no. 2), a = 8.428(2) Å, b = 10.638(3) Å, c = 11.177(3) Å, α = 63.125(4)∘, β = 77.819(4)∘, γ = 79.845(4)∘, V = 869.9(4) Å3, Z = 2, R gt (F) = 0.0472, wR ref (F 2 ) = 0.1379, T = 296(2) K.
Li Yaoyao, Su Lai, Wang Tianqin, Zhang Le   +3 more
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Research on Joint Optimization of Reserve and Dispatching for Multivariety Emergency Materials Based on NSGA-II

Discrete Dynamics in Nature and Society
Emergency material reserve and dispatching are important measures to reduce casualties and property losses after natural disasters occur. However, there has not yet been research that optimizes both the reserve and distribution of emergency materials ...
Xi Zhu, Kai Yao, Aiqiang Guo, Tianpeng Li, Weiyi Wu, Xinbao Gao   +5 more
doaj   +1 more source

Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial

, 2023
Bruno François, Simon Lambden, Tom Fivez, Sébastien Gibot, Marc Derive, Jean‐Marie Grouin, Margarita Salcedo‐Magguilli, Jérémie Lemarie, Nicolas De Schryver, Ville Jalkanen, Tarik Hicheur, Jean–Jacques Garaud, Valérie Cuvier, Ricard Ferrer, Morten H. Bestle, Ville Pettilä, Jean‐Paul Mira, Camille Bouisse, Emmanuelle Mercier, Joris Vermassen, Vincent Huberlant, Isabelle Vinatier, Nadia Anguel, Mitchell M. Levy, Pierre‐François Laterre, Pierre Asfar, Mai-Anh Nay, Christophe Guitton, Jean‐Pierre Quenot, David Tran-Van, Julien Bohé, Gaëtan Plantefève, Saadalla Nseir, Jean‐Yves Lefrant, Xavier Monnet, Laurent Papazian, Christophe Vinsonneau, Jean‐Michel Constantin, Alexandre Mebazaa, Haikel Oueslati, D. Escudero, Fernando Martínez‐Sagasti, Enrique Piacentini, Paula Ramirez Galleymore, Thierry Dugernier, David Fagnoul, Isabelle Michaux, Allan Seibert, Matti Reinikainen, Thorbjørn Grøfte, Ignacio Martín‐Loeches, John G. Laffey   +51 more
openalex   +2 more sources

Measuring the Value of a Statistical Life: Problems and Prospects [PDF]

Tradeoffs between monetary wealth and fatal safety risks are summarized in the value of a statistical life (VSL), a measure that is widely used for the evaluation of public policies in medicine, the environment, and transportation safety.
Ashenfelter, Orley
core   +1 more source