Results 131 to 140 of about 3,112,326 (355)

YTHDF2 in inflammation: Mechanisms and therapeutic strategies

Genes and Diseases
Inflammation is a double-edged sword in biology. Moderate immune responses effectively eliminate pathogens and promote tissue repair, while excessive or persistent inflammation drives acute and chronic diseases.
Junxiu Liu, Senxu Lu, Chuanhuai Chen, Xiaobo Lin, Lijuan Xia, Pansheng Xu, Jinjin Shao, Luxi Yang, Wenhai Huang, Lijiang Zhang   +9 more
doaj   +1 more source

In vitro Antioxidant Activities of Hydroethanolic Extract of Defatted Wonderful Kola (Buchholzia coriacea) Seeds and Its Safety Evaluation in Murine Models

, 2020
Ayokanmi Ore, Regina Ngozi Ugbaja, Abideen Idowu Adeogun, Oluseyi Adeboye Akinloye   +3 more
openalex   +2 more sources

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

DESIGNING AND EVALUATING SOCIAL SAFETY NETS: THEORY, EVIDENCE AND POLICY CONCLUSIONS

, 2004
David Coady, Coady, David P.
openalex   +2 more sources

Lowering blood alcohol content levels to save lives: A European case study [PDF]

Road safety has become an increasing concern in developed countries due to the significant amount of fatalities and the associated economic losses. Only in 2005 these losses rose to 200,000 million euros, a considerable sum approximately 2% of GDP that ...
Daniel Albalate
core   +1 more source

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang, Lu Lu, Hui Gao, Qi Zhang, Jing Xiao, Josemir W. Sander, Weixi Xiong, Dong Zhou   +7 more
wiley   +1 more source

PDG43 SAFETY EVALUATION OF ZOLEDRONIC ACID AND DENOSUMAB USING FDA ADVERSE EVENT REPORTING SYSTEM (FAERS) DATABASE 2012-2018 [PDF]

, 2019
Zizi Elsisi, Andrea Lin, J.J. Guo
openalex   +1 more source

Tracking Foodborne Pathogens from Farm to Table: Data Needs to Evaluate Control Options [PDF]

Food safety policymakers and scientists came together at a conference in January 1995 to evaluate data available for analyzing control of foodborne microbial pathogens. This proceedings starts with data regarding human illnesses associated with foodborne
Anonymous, Jensen, Helen H., Unnevehr, Laurian J.   +2 more
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

In Reply: Pipeline Embolization Device for Treatment of Extracranial Internal Carotid Artery Pseudoaneurysms: A Multicenter Evaluation of Safety and Efficacy [PDF]

, 2020
Krishnan Ravindran, Rabih G. Tawk
openalex   +1 more source