Results 121 to 130 of about 1,128,069 (317)

The crystal structure of methyl 4-(4-(methylsulfonyl)phenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, C19H21NO5S

open access: yesZeitschrift für Kristallographie - New Crystal Structures
C19H21NO5S, triclinic, P1̄ (no. 2), a = 8.428(2) Å, b = 10.638(3) Å, c = 11.177(3) Å, α = 63.125(4)∘, β = 77.819(4)∘, γ = 79.845(4)∘, V = 869.9(4) Å3, Z = 2, R gt (F) = 0.0472, wR ref (F 2 ) = 0.1379, T = 296(2) K.
Li Yaoyao   +3 more
doaj   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Independent Evaluation of Heavy-Truck Safety Applications Based on Vehicle-to-Vehicle and Vehicle-to-Infrastructure Communications Used in the Safety Pilot Model Deployment [PDF]

open access: yes
DTNH22-12-V-00080HS7AThis report presents the methodology and results of the independent evaluation of heavy trucks (HTs) in the Safety Pilot Model Deployment (SPMD); part of the United States Department of Transportation\u2019s Intelligent ...
Najm, Wassim G.   +7 more
core  

Amino Acid and Mineral Element Analysis and Quality Evaluation of Different Color Fruits of Nitraria in Qinghai

open access: yesInternational Journal of Food Science
Only three species of Nitraria fruits are distributed in Qinghai Province, which serve as important berry resources in the desert ecosystem of Qinghai.
Changmao Chen   +5 more
doaj   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

Research on Joint Optimization of Reserve and Dispatching for Multivariety Emergency Materials Based on NSGA-II

open access: yesDiscrete Dynamics in Nature and Society
Emergency material reserve and dispatching are important measures to reduce casualties and property losses after natural disasters occur. However, there has not yet been research that optimizes both the reserve and distribution of emergency materials ...
Xi Zhu   +5 more
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Proceedings of the National Transportation Safety Board Public Forum on Air Bags and Child Passenger Safety [PDF]

open access: yes
The National Transportation Safety Board convened a 4-day public forum from March 17 to March 20, 1997, to discuss concerns related to the effectiveness of air bags, passenger vulnerability to injuries from air bag deployment, other countries' experience
United States. National Transportation Safety Board
core  

Ginsenoside Rh2 regulates cardiomyocyte autophagy-dependent apoptosis through the PI3K-Akt-mTOR signaling pathway to attenuate doxorubicin-induced cardiotoxicity

open access: yesApplied Biological Chemistry
Doxorubicin (DOX)-induced cardiotoxicity has become a major concern and is considered a limitation for the use of DOX in oncology treatment. Ginsenoside Rh2 (Rh2) is a ginseng extract with anti-inflammatory, antioxidant and cell cycle regulating ...
Youping Wu   +5 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

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