Results 141 to 150 of about 3,112,326 (355)

Mission safety evaluation report for STS-31, postflight edition [PDF]

Mission safety factors relative to Space Transportation System (STS) Mission 31 are discussed.
Finkel, Seymour I., Hardie, Kenneth O., Hill, William C.   +2 more
core   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Research on Industrial Safety Evaluation Model under the Restriction of Resources and Environment [PDF]

, 2016
Guoyu Ning, Jingfeng Zhao
openalex   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Determination of nitrite in rifapentine and analysis of the formation causes of nitrosamine impurity

Frontiers in Chemistry
IntroductionDuring drug manufacturing, residual nitrosamine salts in the final formulation are a key contributor to the formation of genotoxic nitrosamine impurities.
Yaodong Ping, Yaodong Ping, Yongxiang Liu, Yongxiang Liu, Hairuo Wen, Nie Wen, Bin Li, Bin Li, Yuan Chen, Ye Tian   +9 more
doaj   +1 more source

Comment on: “A Single Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Orally Administered Des-aspartate Angiotensin I in Healthy Subjects” [PDF]

, 2016
Nuggehally R. Srinivas
openalex   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

CTNI-31. INTERIM RESULTS OF A PHASE I/IIA STUDY TO EVALUATE THE SAFETY AND EFFICACY OF BBB OPENING WITH THE SONOCLOUD-9 IMPLANTABLE ULTRASOUND DEVICE IN RECURRENT GLIOBLASTOMA PATIENTS PRIOR TO IV CARBOPLATIN [PDF]

, 2020
Ahmed Idbaïh, François Ducray, Roger Stupp, Nathalie Baize, Olivier Chinot, John de Groot, Jacques Guyotat, Adam M. Sonabend, Philippe Meneï, Henry Dufour, Jeffrey S. Weinberg, Carole Desseaux, Michael Canney, Charlotte Schmitt, Alexandre Carpentier   +14 more
openalex   +1 more source

Evaluation of pharmacokinetics and safety of talazoparib in patients with advanced cancer and varying degrees of hepatic impairment [PDF]

, 2022
Cen Guo, Yanke Yu, Jayeta Chakrabarti, Sarina A. Piha‐Paul, Rebecca Moroose, Anna Plotka, Haihong Shi, Chandrasekar Durairaj, Diane D. Wang, Zev A. Wainberg   +9 more
openalex   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source