Results 71 to 80 of about 19,469,886 (406)

Increasing Youth Safety and Responsible Behavior Online: Putting in Place Programs that Work. [PDF]

, 2011
Hundreds of programs are being developed to promote safe and responsible online behavior among youth. They are being successfully marketed and eagerly adopted because of their appealing content, exciting graphics, engaging games, catchy phrases and cool ...
Finkelhor, David, Jones, Lisa M.
core   +1 more source

Assurance Benefits of ISO 26262 compliant Microcontrollers for safety-critical Avionics

, 2018
The usage of complex Microcontroller Units (MCUs) in avionic systems constitutes a challenge in assuring their safety. They are not developed according to the development requirements accepted by the aerospace industry.
Forsberg, Håkan, Schwierz, Andreas
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Repeat-dose toxicity of human umbilical cord mesenchymal stem cells via subcutaneous injection in NOG mice

Frontiers in Cell and Developmental Biology
BackgroundStem cell therapy shows promise for treating skin diseases and enhancing medical aesthetics. However, safety data for subcutaneous injection of stem cells remain limited.
Lijuan Xia, Jinjin Shao, Qian Yang, Chengda Zhang, Zhiqi Xie, Linying Wang, Cong Xu, Siming Zhang, Jing Liu, Jing Liu, Fang Liu, Fang Liu, Yuhua Shi, Liqiang Gu, Xiaobo Lin, Jiahong Wang, Ying Chen, Yunxiang Chen, Xin Pan, Feifei Wu, Ruolang Pan, Jinfeng Liang, Lijiang Zhang, Lijiang Zhang   +23 more
doaj   +1 more source

Protocol of the IntenSify‐Trial: An open‐label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab‐paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy [PDF]

, 2023
Nicolas Hohmann, Martin R. Sprick, Moritz Pohl, Azaz Ahmed, Jürgen Burhenne, Marietta Kirchner, Lucian Le Cornet, Markus Kratzmann, Jacek Hajda, Albrecht Stenzinger, Karen Steindorf, Stefan Delorme, Heinz‐Peter Schlemmer, Sabine Riethdorf, Ron van Schaik, Klaus Pantel, Jens T. Siveke, Thomas Seufferlein, Dirk Jäger, Walter E. Haefeli, Andreas Trumpp, Christoph Springfeld   +21 more
openalex   +1 more source

Safety evaluation of low level light therapy on cancer cells [PDF]

, 2016
OBJECTIVE: Low level light therapy (LLLT) is being widely used in wound healing and pain relief, and its use is expected to be expanded rapidly to treatment of other disorders as well in a foreseeable future.
Jeong, Andrew S.
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Human umbilical cord mesenchymal stem cell therapy for atopic dermatitis through inhibition of neutrophil chemotaxis

Stem Cell Research & Therapy
Background Atopic dermatitis (AD) management is significantly challenging due to the high prevalence, chronicity, and recurrent nature of the disease, and limited options for its treatment.
Jinjin Shao, Zhiqi Xie, Zhichao Ye, Guoyu Chen, Yiru Wang, Lili Zhang, Fang Liu, Siming Zhang, Xiaobo Lin, Jiahong Wang, Ying Chen, Yunxiang Chen, Xin Pan, Feifei Wu, Ruolang Pan, Jinfeng Liang, Lijiang Zhang   +16 more
doaj   +1 more source

762 A first-in-human phase 1 clinical study evaluating safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of the EDB+FN targeting ADC PYX-201 in participants with advanced solid tumors [PDF]

, 2023
Sharon Wilks, Benedito A. Carneiro, Gregory M. Coté, Jason T. Henry, Shiraj Sen, Alexander I. Spira, Frank Tsai, Judy S. Wang, Marsha Crochiere, Shui He, Sondra Smyrnios, Dipali Unadkat, Bin Zhang, Anthony W. Tolcher   +13 more
openalex   +1 more source

Generalized safety equation - A concept [PDF]

, 1971
Concept provides definition of relationship between safety and reliability, personnel safety measurement, and equipment safety evaluation. Safety systems cope with single or combined risks.
Hano, G.
core   +1 more source