Results 81 to 90 of about 19,469,886 (406)

Map-Guided Curriculum Domain Adaptation and Uncertainty-Aware Evaluation for Semantic Nighttime Image Segmentation

, 2021
We address the problem of semantic nighttime image segmentation and improve the state-of-the-art, by adapting daytime models to nighttime without using nighttime annotations.
Dai, Dengxin, Sakaridis, Christos, Van Gool, Luc   +2 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Developmental and reproductive toxicity assessment of sporoderm-removed Ganoderma lucidum spores

Frontiers in Cell and Developmental Biology
IntroductionGanoderma lucidum is a fungus used in traditional Chinese medicine with high medicinal value and is also widely used in modern healthcare. Its spores are reported to contain antitumor and anti-inflammatory properties, among other biological ...
Junxiu Liu, Yisheng Song, Yisheng Song, Chuanhuai Chen, Jing Liu, Jing Liu, Siming Zhang, Fang Liu, Fang Liu, Ruiyu Tian, Jinjin Shao, Lili Zhang, Tingli Bian, Ruimin Sun, Li Yu, Shuizhen Pan, Yunxiang Chen, Yaoxian Xuan, Hanbo Wang, Zhenhao Li, Ying Chen, Lijiang Zhang, Lijiang Zhang   +22 more
doaj   +1 more source

Safety evaluation of the food enzyme glucan 1,4‐α‐glucosidase from Aspergillus niger [PDF]

, 2022
Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Boet Glandorf, Lieve Herman, Jaime Aguilera, Natália Kovalkovičová, Yi Liu, Andrew Chesson, Andrew Chesson   +22 more
openalex   +1 more source

Exploratory study into a safety format for composite columns exposed to fire [PDF]

, 2019
Current performance based structural fire engineering approaches evaluate structural behaviour under prescribed fire scenarios. The mechanical properties of the materials, the load conditions and geometric parameters are all however fraught with ...
Elhami Khorasani, Negar, Gernay, Thomas, Hopkin, Danny, Van Coile, Ruben   +3 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Evaluation of Safety of Reinforced Concrete Buildings to Earthquakes [PDF]

, 1976
National Science Foundation Grant GK ...
Ang, A.H-S., Portillo Gallo, M.
core  

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Bio-distribution and toxicity potential of human umbilical cord mesenchymal stem cells in cynomolgus monkeys

Scientific Reports
Mesenchymal stem cells (MSCs) have demonstrated promising advantages in the therapies of many diseases, while its multi-directional differentiation potential and immunotoxicity are the major concerns hindered their clinical translation.
Ying Huang, Xiaofang Hao, Zhi Lin, Lulu Li, Hua Jiang, Hezhan Zhang, Xingchao Geng, Hao Zhu, Hairuo Wen   +8 more
doaj   +1 more source