Results 41 to 50 of about 323,756 (267)

Omics-Based Analytical Approaches for Assessing Chicken Species and Breeds in Food Authentication

Molecules, 2021
Chicken is known to be the most common meat type involved in food mislabeling and adulteration. Establishing a method to authenticate chicken content precisely and identifying chicken breeds as declared in processed food is crucial for protecting ...
Goh Dirong, Sara Nematbakhsh, Jinap Selamat, Pei Pei Chong, Lokman Hakim Idris, Noordiana Nordin, Fatchiyah Fatchiyah, Ahmad Faizal Abdull Razis   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Inspection and testing methodology for safety instrumented system of oil and gas pipeline

You-qi chuyun
Objective The flourishing construction and rapid development of smart pipeline networks and unattended stations have elevated the requirements for oil and gas pipelines and stations, particularly in terms of safety and reliability.
Yu DIAO, Qiujuan LI, Zhaoyang LIU, Zifeng YU, Fengyin ZHANG, Dongyang LI, Shan HUANG, Ye TAO   +7 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Integral Approach to Safety

International Journal of Engineering Technology and Sciences, 2016
There is a need to balance the reliance on a traditional OSHMS being implicitly adhered to against the human contribution factor. The aim of this qualitative study paper is to describe and discuss the existing leadership styles and approaches that are being practiced and past initiatives that have produced results in OSH performance.
Dzulqarnain Bin Abu Bakar, Norazura Binti Ismail   +1 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Antibiotic and Cu2+ Co-Selection in MFCs Treating Swine Wastewater: Antibiotic Resistance Genes Dynamics and Removal Performance

Environmental Chemistry and Safety
Intensive livestock production relies heavily on sulfonamides, quinolones and Cu/Zn additives, creating potent co-selective pressures that accelerate the environmental spread of antibiotic-resistance genes (ARGs).
Weidong Shang, Yufei Liu, Dongle Cheng, Huu Hao Ngo, Wenshan Guo, Huaqing Liu, Lin Li, Xinhan Chen, Congcong Liu   +8 more
doaj   +1 more source

Integrated safety in tocilizumab clinical trials [PDF]

Arthritis Research & Therapy, 2011
Abstract Introduction The efficacy and safety of tocilizumab in patients with rheumatoid arthritis have been evaluated in a comprehensive phase 3 program. Patients from these randomized trials could receive tocilizumab treatment in open-label extension trials.
Schiff MH, Kremer JM, Jahreis A, Vernon E, Isaacs JD, van Vollenhoven RF   +5 more
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A framework for integrated safety in safety-management systems in healthcare

International Journal of Health Governance
Purpose Notwithstanding increased patient safety initiatives, adverse events and their impact on those involved continue. The strategic approaches adopted to manage safety by other high-intensity, high-risk and complex industries, such as aviation, have led to an increase in the systems approach for safety ...
Patricia Vella Bonanno, Einav Srulovici, José Joaquín Mira, Reinhard Strametz, Susanna Tella, Valentina Marinkovic, Anat Rafaeli, Mary Elizabeth Tumelty, Andreas Pitz, Sofia Guerra Paiva, Anu Venesoja, Sandra C. Buttigieg   +11 more
openaire   +4 more sources