Results 81 to 90 of about 251,357 (265)

Representing the Fuzzy improved risk graph for determination of optimized safety integrity level in industrial setting

open access: yesبهداشت و ایمنی کار, 2013
Introduction: Due to the presence of extreme hazard sources and high intrinsic risk in refineries and process industry sectors, different layers of protection are being used to reduce the risk and avoid the hazardous events.
Z. Qorbali   +3 more
doaj  

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Safety Integrity Level Assessment and Certification of Localization Train Network Control Management System

open access: yes机车电传动, 2011
In this paper, on the basis of analyzing the core work for train network control system SIL certification, the key contents of SIL assessment activity process in TCMS development safety lifecycle were summarized, and a specific method for the SIL index ...
赵强, 常振臣, 李砾工, 王金田
doaj  

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong   +10 more
wiley   +1 more source

Quantitative Analysis and Allocation of Safety Integrity Level Indexes for Urban Rail Transit Vehicle System

open access: yesChengshi guidao jiaotong yanjiu
Objective Development and application of FAO (fully automatic operation)system in urban rail transit train requires higher safety of urban rail vehicle system.
QIN Jiaomei, PAN Demin, FAN Kaijiang
doaj   +1 more source

Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Safety Lifecycle of Safety Instrumented System

open access: yesAlgerian Journal of Signals and Systems
In this article, we explored the safety lifecycle of the Safety Instrumented System (SIS). First, we introduced the SIS, its Safety Instrumented Function (SIF), its Safety Integrity Level (SIL) and its Safety Lifecycle.
Nabil BOUDJOGHRA, Fares INNAL
doaj   +1 more source

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