Results 111 to 120 of about 4,898,935 (299)
The effect of resistance exercise on strength and safety outcome for people with haemophilia: A systematic review. [PDF]
Haemophilia, 2020 Wagner B +6 more
europepmc +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Design-Based Safety: The Evolution of Safety
, 2015 The word “safety” has a variety of meanings. It is a condition of being free from “accidents,” or any device for preventing an accident. The word “accident” means “unintended event,” and does not reveal that there is a cause created by a “hazard.” In ...
MacCollum, David
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Treatment-related damage in elderly-onset ANCA-associated vasculitis: safety outcome analysis of two nationwide prospective cohort studies. [PDF]
Arthritis Res Ther, 2020 Sada KE +20 more
europepmc +1 more source
System Safety Bookshelf: Applying Safety Standards to Life-Saving Equipment
, 2019 Elsevier Academic Press has recently published a new safety book titled Safety Risk Management for Medical Devices, written by Bijan Elahi. This book explains how to conduct a risk management program that will show conformance to the FDA safety standards
Ericson, Clif
core +1 more source
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
The Influence of Safety Ownership on Occupational Road Safety Outcomes
Journal of Road Safety, 2010 Questionnaires and interviews were conducted with employees and senior managers from three Australian organisations to explore the relationship between perceived managerial ownership of safety responsibilities and occupational road safety. It was found that the perceived authority of the person primarily responsible for managing road risks and ...
Banks, Tamara D +2 more
openaire +1 more source
An Investigation of Safety Training and Safety Outcome in a Manufacturing Plant
Jurnal Teknologi, 2013 Safety training is considered as one of safety intervention that is believed to be an antecedent of safety outcome within organization. The rapid advancement in safety management field has also raised many questions mainly to the roles of safety training in organizations safety.
openaire +1 more source
Scientific ReportsFruit juice is a widely consumed non-alcoholic beverage, particularly by children in developing countries. However, prolonged consumption can lead to the accumulation of toxic metals in the body, potentially increasing the risk of carcinogenesis.
Fasika Weldegebriel +6 more
doaj +1 more source