Results 41 to 50 of about 2,284 (202)

Seasonality and hydrodistillation time effects on the yield and chemical composition of leaves essential oil of Piper mikanianum (Kunth) Steudel

Eclética Química, 2018
Piper mikanianum from Santa Catarina, southern Brazil, is a well known source of safrole, an arylpropanoid precursor of several bioactive molecules. This work determined the seasonal and hydrodistillation time influence on the essential oil (EO) yield ...
Sabrina M. Clemes, Thalita G. Santos, Ricardo A. Rebelo, Rudi R. Laps, Rosete Pescador   +4 more
doaj   +1 more source

GC/MS-MID Determination of Safrole in Soft Drinks [PDF]

, 2002
Safrole [1,3-benzodioxole, 5-(2-propenyl)-] is a limited substance according to the CE Directives N. 88/388 and 91/71 concerning “flavourings for use in foodstuffs and to source materials for their production”. At today the GC analytical methods proposed
F. Tateo, S. Fasan, A. Fossati, M. Bononi, E. Lubian   +4 more
core   +2 more sources

Insights into structural, vibrational, and chemical shift characteristics, solvents impact (polar and nonpolar) on electronic properties and reactive sites, ADMET predictions, and ligand-protein interactions for antiviral drugs safrole and isosafrole: An in-silico approach

Chemical Physics Impact
The safrole and isosafrole are constitutional isomers that have been theoretically characterized utilizing Density Functional Theory (DFT) employed with the B3LYP/6-311++G(d,p) basis set to simulate geometrical parameters, vibrational aspects, electronic
A. Ram Kumar, S. Selvaraj, P. Rajkumar, J. Dhanalakshmi, Mohanraj Kumar, Senthil Kumar Nagarajan, P. Jayaprakash, G.P. Sheeja Mol, Shikha Awasthi, Sarvesh Kumar Pandey   +9 more
doaj   +1 more source

Safrole Induces Apoptosis in Human Oral Cancer HSC-3 Cells

, 2014
Phytochemicals have been used as potential chemopreventive or chemotherapeutic agents. However, there are data suggesting a mutagenic effect of some phytochemicals.
Lu, C.C., Lin, C.W., Yang, J.S., Chung, J.G., Yu, C.S., Yu, F.S., Chiang, J.H.   +6 more
core   +2 more sources

Genetic divergence of Piper hispidinervum C. DC. populations concerning morphoagronomic traits

Pesquisa Agropecuária Tropical, 2013
In order to generate information for the Piper hispidinervum breeding program, in the Acre State, Brazil, the genetic divergence among fifteen populations collected in different regions of the State was evaluated.
Jacson Rondinelli da Silva Negreiros, Daniela Popim Miqueloni   +1 more
doaj   +1 more source

The Chemical Profiling of Essential Oils from Different Tissues of Cinnamomum camphora L. and Their Antimicrobial Activities

Molecules, 2021
Cinnamomum camphora L. is grown as an ornamental plant, used as raw material for furniture, as a source of camphor, and its essential oil can be used as an important source for perfume as well as alternative medicine.
Darbin Kumar Poudel, Anil Rokaya, Pawan Kumar Ojha, Sujan Timsina, Rakesh Satyal, Noura S. Dosoky, Prabodh Satyal, William N. Setzer   +7 more
doaj   +1 more source

Synthesis of a New α-Azidomethyl Styrene from Safrole via a Dearomative Rearrangement

Molbank, 2023
There is a growing interest in developing more efficient synthetic alternatives for the synthesis of nitrogen-containing allylic compounds. This article presents a straightforward two-step protocol to produce 5-(3-azidoprop-1-en-2-yl)benzo[d][1,3]dioxole
Stephen R. Isbel, Alejandro Bugarin
doaj   +1 more source

Mitochondrial Mediated Apoptosis Evaluation of Myristicin on Triple Negative Breast Cancer Model Via Bcl2/Bid Pathway

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT Among 15‐20 cases of breast cancer, triple‐negative breast cancer (TNBC) is the deadliest form of the disease. The most effective form of treatment for this type of cancer is still targeted chemotherapy because it lacks hormone receptors. Myristicin, an active aromatic compound with anticancer properties, is mostly found in nutmeg.
Sudhina Sufina Nazar, Aswathy Vadakkumkattle Ajaykumar, Janeesh Plakkal Ayyappan   +2 more
wiley   +1 more source

Ligand binding of safrole to cytochrome P-450.

, 2020
Safrole, a hepatocarcinogen, is converted by the microsomal mono-oxygenase system to a reactive intermediate which interacts with cytochrome P-450 to form a ligand complex.
Parke, DV, Delaforge, M, Ioannides, C
core   +1 more source

Antioxidant and Cytotoxic Properties of Piper spp. Volatile Oils That Inhibit Pathogenic Microorganisms

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 935-942, July 2026.
The samples were fungicidal against Candida, with MICs ranging from 62.5 to 250 μg/mL, and fungistatic against Penicillium adametzii, Aspergillus flavus and A. niger, with MICs of 1000 μg/mL. The volatile oils of Piper aduncum and Piper marginatum reduced the viability of MDA‐MB231 cells.
Midiã R. Oliveira, Ely D. Alfaia Neto, Carlos Eduardo C. Alves, Renata Galvão de Azevedo, Alice F. Gomes, Flávia Juliana Reis de Sousa, Juan Campos de Oliveira, Larissa Raquel S. Maciel, Gemilson S. Pontes, Ari F. Hidalgo, Antonia Q. L. Souza, Rita C. Saraiva Nunomura   +11 more
wiley   +1 more source