Results 91 to 100 of about 53,920 (249)

MagGami: An Electromagnetic Origami Actuator With High Stiffness‐Switching Density for Lightweight Joint‐Space Wearable Haptics

open access: yesAdvanced Science, EarlyView.
Concept of the MagGami‐based joint‐space haptic glove. a) Comparison between Cartesian‐space fingertip force feedback and distributed joint‐space torque feedback, highlighting the limitations of representative motor‐driven, pneumatic, and smart material‐based haptic actuators.
Tianhao Jin   +9 more
wiley   +1 more source

Long‐Term Expandable Periosteal Organoids Reconstruct a Functional Regenerative Niche That Support Hematopoietic Stem Cell Maintenance and Bone Repair

open access: yesAdvanced Science, EarlyView.
A robust periosteal organoid system enables long‐term expansion while preserving native cellular heterogeneity. These organoids recapitulate functional niche environments, support hematopoietic stem cell maintenance, and attenuate aging‐associated decline ex vivo.
Jia Qing   +9 more
wiley   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

open access: yesAdvanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao   +8 more
wiley   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Convergence on a Senescence‐Associated B Cell–MIF Signaling Axis in Joint Aging and Osteoarthritis Progression

open access: yesAdvanced Science, EarlyView.
Single‐cell and spatial transcriptomics implicate senescent B cells and macrophage migration inhibitory factor (MIF) signaling in aging and osteoarthritic joints. An injectable hydrogel combining quercetin with siRNA targeting MIF attenuates cartilage degeneration in a mouse model of osteoarthritis.
Weida Li   +11 more
wiley   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

open access: yesAdvanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong   +5 more
wiley   +1 more source

Association of Craniocervical Sagittal Alignment With the Outcomes of Cervical Disc Replacement

open access: yesGlobal Spine Journal
Study Design Retrospective cohort study. Objective To explore the association between craniocervical sagittal balance and clinical and radiological outcomes of cervical disc replacement (CDR).
Yi-Wei Shen MD   +8 more
doaj   +1 more source

A High‐Precision Dynamic Movement Recognition Algorithm Using Multimodal Biological Signals for Human–Machine Interaction

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This article describes a multimodal fusion data acquisition and processing system about electromyography for dynamic movement recognition and bioelectrical impedance for key posture recognition. In addition, a new dynamic–static fusion algorithm strategy is designed.
Chenhao Cao   +5 more
wiley   +1 more source

Continuous and Large‐Scale: ELEANOR, the Soft Architected Arm Inspired by the Elephant Trunk

open access: yesAdvanced Intelligent Systems, EarlyView.
A large‐scale, architected continuum robot inspired by the macroscopic properties of the African elephant trunk achieves adaptive elephant‐like movements and whole‐body grasping. The results demonstrate that designing from the natural system’s macroscopic properties, rather than prescribing behaviors, provides a powerful strategy for developing ...
Giovanna A. Naselli   +8 more
wiley   +1 more source

The Key Technologies and Technological Evolution Mechanisms of Robotic Systems for Fracture Reduction Surgery

open access: yesAdvanced Intelligent Systems, EarlyView.
This review traces three decades of technological evolution in robot‐assisted fracture reduction systems, from early robotic concepts to clinically oriented platforms. Key advances in robotic architecture, navigation, path planning, interaction control, and surgical integration are summarized, while current translational challenges and future ...
Shaolong Kuang   +5 more
wiley   +1 more source

An Active Knee–Ankle–Foot Orthosis With Torque‐Dense, Low‐Impedance Knee Actuation

open access: yesAdvanced Intelligent Systems, EarlyView.
This article presents the simulation, design, and clinical validation of a robotic active KAFO with torque‐sensitive actuation. By passively and continuously adapting the transmission ratio in response to the knee torque, the torque‐sensitive actuator overcomes the tradeoff between torque, weight, and impedance observed in conventional robot actuators,
Brendon Ortolano   +4 more
wiley   +1 more source

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