Results 71 to 80 of about 53,920 (249)

How does the sagittal spinal balance of the scoliotic population deviate from the asymptomatic population?

BMC Musculoskeletal Disorders, 2018
Background Previously, the sagittal spinal balance in both asymptomatic and scoliotic Caucasian people has been characterized and compared. Very recently, the sagittal spino-pelvic parameters among asymptomatic Chinese adults have been studied, and the ...
Pan-pan Hu, Miao Yu, Xiao-guang Liu, Zhong-qiang Chen, Zhong-jun Liu   +4 more
doaj   +1 more source

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

Advanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li, Xi Wan, Xinru Su, Zechuan Li, Yue Wang, Ying Wang, Ruofei Li, Huangzhao Wei, Jianbin Zhang, Shuai Wang   +9 more
wiley   +1 more source

Fumarate Hydratase Lactylation Exacerbates Traumatic Brain Injury Pathology via Mitochondrial Dysfunction and Neuroinflammation

Advanced Science, EarlyView.
Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian, Shuoyao Ma, Bo Yang, Fei Gao, Hao Guo, Haixiao Liu, Xun Wu, Wenxing Cui, Jingyu Dong, Qian Lin, Yufeng Ge, Jin Ma, Jiazhen Zhao, Yongzhi Zhang, Dongzhi Xue, Jiaxin Tian, Ziwen Zhang, Kai Wang, Meng Xu, Dayun Feng, Jinpeng Zhou, Yan Qu   +21 more
wiley   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Does dynamic balance affect cube mental rotation task in badminton vs. volleyball female players?

BMC Psychology
Background Changing from a static to a dynamic balance condition could affect the performance of a cognitive task such as mental rotation. Thus, the main goal of this study is to investigate aspects of visual-spatial cognition between two non-contact ...
Samiha Amara, Badriya Al-Hadabi, Heba El-Ashkar, Nabil Gmada, Hamdi Habacha, Bessem Mkaouer   +5 more
doaj   +1 more source

Sagittal spinal alignment in adolescent idiopathic scoliosis: a narrative review of pre- and post-treatment characteristics

EFORT Open Reviews
Adolescent idiopathic scoliosis (AIS) involves significant sagittal plane abnormalities, most consistently characterized by reduced thoracic kyphosis (TK), with compensatory changes in lumbar lordosis (LL) and cervical lordosis (CL).
Yu Song, Yimin Yan, Cao Yang, Kun Wang
doaj   +1 more source

Lenke 1 and 5: changes in sagittal balance

Coluna/Columna, 2014
OBJECTIVE: To assess in a cross-sectional study whether there are changes in sagittal balance in patients with adolescent idiopathic scoliosis Lenke types 1 and 5 compared with patients without pathology of the spine and compare the values of the ...
Delson Valdemir Pessin, José Osni Bruggemann Neto, Carlos Henrique Maçaneiro, Ricardo Kiyoshi Miyamoto, Rodrigo Fetter Lauffer, Ricardo Acácio dos Santos   +5 more
doaj   +1 more source

scGEN: Leveraging an Adaptive Weighting Strategy for Challenging Cell Clustering in Single‐Cell RNA‐seq

Advanced Science, EarlyView.
scGEN combines attribute–structure encoding, adaptive hard‐sample weighting, and regularized zero‐inflated negative binomial loss to resolve ambiguous single‐cell states. In the developing human pituitary, refined annotations reveal Pre.Gonado cells at 7 weeks and previously obscured developmental communication networks.
Fang Huang, Dayu Hu, Yaqi Dai, Aoyi Geng, Renxiang Guan, Hao Quan, Brett A. McGregor, Zhihan Wang, Nadeem Khan, Hongsheng Zhang, Jinghua Zhang, Mingyang Xia, Xiaoqiong Gu, Di Che, Junguk Hur, Xiaoyu Cui, Kai Guo   +16 more
wiley   +1 more source

How does cervical sagittal profile change after the spontaneous compensation of global sagittal imbalance following one- or two-level lumbar fusion

BMC Musculoskeletal Disorders
Purpose This study aimed to evaluate the cervical sagittal profile after the spontaneous compensation of global sagittal imbalance and analyze the associations between the changes in cervical sagittal alignment and spinopelvic parameters. Methods In this
Chengxin Liu, Weiguo Zhu, Yongjin Li, Xiangyu Li, Bin Shi, Chao Kong, Shibao Lu   +6 more
doaj   +1 more source

The Effect of Schroth Exercises and Orthotic Bracing on Changes in Sagittal Balance and Sagittal Index in Patients with Adolescent Idiopathic Scoliosis

Exercise and Quality of Life
Introduction: Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity characterized by lateral curvature, vertebral rotation, and sagittal imbalance.
Nikola Jevtić, Vanja Dimitrijević, Bojan Rašković, Samra Pjanić, Theodoros B. Grivas, Nachiappan Chockalingam, Borislav Obradović   +6 more
doaj   +1 more source