Results 121 to 130 of about 673,928 (344)

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

БУКОВИНСЬКІ ВЕЛИКОДНІ ПИСАНКИ: ІСТОРІЯ І СУЧАСНІСТЬ / Bukovyna easter pysanky: history and contemporaneity

open access: yesАктуальні питання суспільних наук та історії медицини, 2014
Kojolianko Alexander. BUKOVYNA EASTER PYSANKY: HISTORY AND CONTEMPORANEITY The personal touches of Bukovyna pysankarstva are investigational in the article.
Кожолянко Олександр
doaj  

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

“Los francmasones franceses de la jurisdicción de Cuba al principio del siglo XIX”

open access: yesREHMLAC, 2009
Con la técnica de la prosopografía, este artículo pro pone presentar las características de los masones franceses, antiguos colonos de Saint-Domingue refugiados en Santiago de Cuba, al principio del siglo XIX.
Agnès Renault
doaj  

Home - About - Disclaimer - Privacy