Results 161 to 170 of about 673,928 (344)

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis   +17 more
wiley   +1 more source

Hospital Care and the Conception of Death in the Hospitaller Order of Saint John of God in Sixteenth- and Seventeenth-Century Spain. [PDF]

Nurs Inq
Muñoz Devesa A, Rico Becerra JI.
europepmc   +1 more source

Saints, Sinners, and Psychiatry

, 1952
Jean C. Bloom, Camilla M. Anderson
openalex   +2 more sources

Saint-Félix (Charente). Saint-Félix

Archéologie médiévale, 2013
Plisson, Sophie, Plisson, Sophie
openaire   +3 more sources

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Nematopsis Schneider, 1892 in Nerite Gastropods From Saint Kitts, With a Phylogenetic Study of the Genus, and Placement Within the Phylum Apicomplexa Levine, 1970. [PDF]

J Eukaryot Microbiol
Herbert NAM, Kristmundsson Á, Vazquez N, Hoag K, Freeman MA.   +4 more
europepmc   +1 more source

Sopra alcune limitazioni per la sollecitazione elastica e sopra la dimostrazione del principio del De Saint Venant [PDF]

, 1931
Giulio Supino
openalex   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

To the Editor: In Expectation of a More Evidence-Informed Perspective on Emergency Medicine Education. [PDF]

J Grad Med Educ
Chukwuanu KA, Burkhartsmeier C, Krausz C.   +2 more
europepmc   +1 more source

The Holy Catholic Church. The Communion of the Saints. A Study in the Apostle's Creed. Henry Barclay Swete [PDF]

, 1916

openalex   +1 more source