Results 31 to 40 of about 12,248 (340)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Santos e devotos no império ultramarino português

open access: yesReligião e Sociedade, 2009
O artigo faz uma história da coleção de vilancicos de São Gonçalo de Amarante, que integram a Coleção Barbosa Machado na Biblioteca Nacional do Rio de Janeiro e, simultaneamente, apresenta reflexões sobre a relação santo-devoto no Império Ultramarino ...
Beatriz Catão Cruz Santos
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Tasavvufa Yönelik Eleştiriler Bağlamında “Velâyet” Kavramının Kaynaklarda Ele Alınışı

open access: yesTasavvuf İlmi ve Akademik Araştırma Dergisi, 2021
Tasavvuf, tarih boyunca bir taraftan İslam’ın yayılmasında önemli görevler icra etmiş, diğer taraftan Müslümanların büyük kırılmalar yaşadığı dönemlerde, onları ümmet şuuru ile bir arada tutup yeniden toparlanmalarını sağlamıştır.
Mehmet Şirin Ayiş
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Creating Josaphat: The Making of a Saint in the Church-Slavonic Office for Josaphat Kuntsevych

open access: yesLietuvos Istorijos Studijos
The liturgical commemoration of Josaphat Kuntsevych, the Uniate Archbishop of Polatsk, was initiated soon after his death in the hands of Orthodox citizens in Vitsyebsk in 1623. The hymnographical Office (sluzhba) for Josaphat developed in the course of
Maria Takala-Roszczenko
doaj   +1 more source

La falsa santità – il caso di Sibilla di Marsal

open access: yesSeminare, 2022
The object of this study is Sybilla of Marsal, a woman who lived in the 13th-century France. Her story was first described by Richer of Senones in Gesta Senoniensis Ecclesiae.
Anna Głusiuk
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Shaping Charisma: Muda Waly al-Khalidi and Saint-Making in Contemporary Indonesia

open access: yesMillati: Journal of Islamic Studies and Humanities
This article aims to clarify the social process of creating waliyullah in Muslim society. Waliyullah is often considered the highest prestige acquired by a mere human other than the Messenger.
Sehat Ihsan Shadiqin
doaj   +1 more source

A charming symmetry : Pompilia's multiplicity : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in English at Massey University [PDF]

open access: yes, 1987
This thesis examines Pompilia's monologue in The Ring and the Book. William Walker's article " 'Pompilia' and Pompilia" notes that criticism is unified in its assessment of Pompilia's monologue despite being divergent on other issues concerning the ...
Sutton, Tina Marie
core  

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