Results 121 to 130 of about 279,940 (313)
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Paraphysical Jurisprudent Massacre Mediation [PDF]
, 2015 It is possible and thereby feasible to develop and implement a pragmatic methodology for a preemptive evidentiary system of ‘Paraphysical Jurisprudence’ for mediating the occurrence of massacres.
Amoroso Richard, L.
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Dead Men Talking: Ibn ‘Arabī’s Interactions with Messengers and Saints
ReligionsThe mystical thinker Muhyi al-Din ibn ‘Arabī (d. 638/1240) had many audiences with the dead. This article explores who Ibn ‘Arabī interacted with, and how.
Ismail Lala
doaj +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
, 2019 Excerpt: In his book The Path of Perfect Love, Diogenes Allen suggests that it is because of our inability to perceive the reality of other people and things that we don’t grasp what brings out the fundamental feature of love, viz.
McLeod-Harrison, Mark S.
core
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
St. Genevieve in the Revolution : Sylvain Maréchal’s Counter-History
Conserveries Mémorielles, 2013 Dr. Delany is author of many articles and books in medieval and early modern literature and culture including on Chaucer, Christine de Pizan, Elias Levita and others.
Sheila Delany
doaj
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
, 2015 Jon Boorstin proposes three purposes for film production – voyeuristic, vicarious, and visceral (Boorstin). Scrutinized in light of Boorstin’s proposal, hagiographical films are most likely to have three purposes imbedded in three generic types ...
Yang, Sunggu
core