Results 201 to 210 of about 63,534 (267)

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Effects of nicotinic receptor antagonism on nicotine and THC self-administration in a model of polysubstance use. [PDF]

Int J Neuropsychopharmacol
Torregrossa MM, Racic T, Baglot SL, Stringfield SJ, Hill MN, Sved A.   +5 more
europepmc   +1 more source

A New Metal‐Ester Bonding Motif for the Synthesis of Hybrid Molecular Catalysts on Metal Oxide Supports Leads to Tunable Reactivity

Angewandte Chemie, EarlyView.
This work reports a new metal–ester bonding strategy for anchoring molecular catalysts to metal oxide supports, achieving exceptionally high surface loadings. Catalyst reactivity is predictably tuned by the support's properties, enabling control over electronic behavior and reaction pathways, thus opening new possibilities for designing highly ...
Joseph J. Kuchta III, Sarah M. Moody, Alexia M. Bradbury, D. M. S. C. Dissanayake, Laura C. Maybach, Santosh K. Balijepalli, John R. Regalbuto, Aaron K. Vannucci   +7 more
wiley   +1 more source

Efficacy of a Salt Substitute on the Incidence of Hypertension: A Systematic Review with Meta-Analysis. [PDF]

Arq Bras Cardiol
Kelly FA, Dantas CR, Sobreira LER, Almeida AM, Bezerra FB, Sousa MG, Consolim F, Laurinavicius AG.   +7 more
europepmc   +1 more source

Inhibition and Formation of Amyloid Fibrils in the Bulk and at the Interface of Biomolecular Condensates

Angewandte Chemie, EarlyView.
In this review, we discuss how biomolecular condensates can inhibit amyloid aggregation in their interior, while still facilitating fibril formation at the interface between the dense and dilute phases, where molecular and mesoscale properties are likely optimal to promote protein aggregation.
Marcell Papp, Chiara Morelli, Sarah Khawaja, Paolo Arosio   +3 more
wiley   +1 more source

Salvianolic acid B functionalized injectable GelMA hydrogel for pulpitis in a vital pulp therapy: a dual anti-inflammatory property and enhanced reparative dentinogenesis activity material. [PDF]

BMC Oral Health
Li Z, Xu D, Huang X.
europepmc   +1 more source

Total Chemical Synthesis of Interleukin‐15 and Interleukin‐2: Taming Protein Hydrophobicity and Aggregation by a Versatile Solubilizing Strategy

Angewandte Chemie, EarlyView.
A reducible solubilizing tag strategy (RST‐2.0) enables the synthesis, purification and ligation of difficult peptides while being readily removable just during folding, which overcomes the common challenges from protein hydrophobicity and aggregation. With this method, we achieved the first total synthesis of native and N‐glycosylated IL‐15 as well as
Jingwen Zeng, Haiyan Zhou, Wang Xia, Hongxiang Wu, Xuechen Li   +4 more
wiley   +1 more source

Salidroside protects against high-altitude hypoxia-induced kidney injury via regulation of renal dopamine D1-like receptors. [PDF]

PLoS One
Huan C, Zhilin G, Dan X, Yue W, Xianglian L, Liwen M, Yue C.   +6 more
europepmc   +1 more source

Salidroside mitigates cognitive deficits in AlCl₃ exposed aging mouse by modulating APP processing and mitochondrial dysfunction. [PDF]

Front Behav Neurosci
Dong Y, Jin H, Wang S, Xu Y.
europepmc   +1 more source

Evaluation of bamboo biomass pellets: impact of binder type and age of bamboo on pellet quality and performance. [PDF]

Sci Rep
Ilorkar VM, Raut PD, Nimbarte SR, Deshmukh AP, Pandiyan K, Bhosale AD, Kaple SU.   +6 more
europepmc   +1 more source