Deactivation of CK1α enhances the anti-cancer effects of salinomycin in colorectal cancer HCT116 cells. [PDF]
Biochem Biophys RepKhakshournia S +7 more
europepmc +1 more source
Associations between inclusive community coalition leadership and use of evidence‐based practices
American Journal of Community Psychology, EarlyView.Abstract Community coalitions have the potential to elicit diverse participants' perspectives on complex issues and generate shared commitment to adaptive strategies. Ideally, these approaches have been found effective elsewhere. Despite evidence that leadership plays a generally important role in coalitions, there have been limited prior findings ...
Rebecca Wells +4 more
wiley +1 more source
Investigating the Role of Salidroside in Alleviating Acute Pancreatitis by Inhibiting the RIPK1/RIPK3/MLKL Pathway-Mediated Necroptosis in Pancreatic Acinar Cells in Rats. [PDF]
J Inflamm ResLin Y, Ma X, Zhang L, Gu H, Fu X, Li P.
europepmc +1 more source
American Journal of Hematology, EarlyView.ABSTRACT The addition of midostaurin (MIDO) to intensive chemotherapy (IC) improves survival in younger adults with FLT3‐mutated acute myeloid leukemia (AML); however, real‐world data in elderly patients (≥ 60 years) are limited. This large, retrospective, multicenter study from three European registries (PETHEMA, FILO, DATAML) evaluated MIDO+IC (n ...
Gaspar Aspas Requena +31 more
wiley +1 more source
Retraction: MicroRNA-181b Inhibits Cellular Proliferation and Invasion of Glioma Cells via Targeting Sal-Like Protein 4. [PDF]
Oncol ResOncology Research Editorial Office.
europepmc +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Mosaicism is relatively common in Tuberous Sclerosis Complex (TSC) but can be difficult to detect using routine diagnostic tests, particularly when the variant allele frequency (VAF) is low. We describe two cases of mosaic TSC diagnosed using an ultra‐deep sequencing approach in multiple tissues and review the literature about this topic in ...
Irene Ambrosetti +14 more
wiley +1 more source
SAL-YOLO-DeepSeek: a lightweight real-time detection and LLM-driven decision framework for intelligent escalator safety monitoring. [PDF]
Sci RepWang Q +6 more
europepmc +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT To evaluate the prevalence of psychiatric signs and symptoms and describe psychotherapeutic and psychopharmacological interventions among children with osteogenesis imperfecta (OI). PRISMA guidelines were followed, and the study was registered in PROSPERO (CRD42024588284). Studies (n = 1419) were identified across five databases.
Julia M. Morales +13 more
wiley +1 more source
Protein synthesis blockade prevents fear memory reactivation via inhibition of engram synapse strengthening. [PDF]
Proc Natl Acad Sci U S AHong I +5 more
europepmc +1 more source
Genetic and Phenotypic Features of the Five Known Polyaminopathies: A Critical Narrative Review
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Polyaminopathies are a recently described family of rare genetic neurodevelopmental disorders. Polyaminopathies disrupt the biosynthesis of the primary polyamines: putrescine, spermidine, and spermine. Snyder–Robinson syndrome results from hemizygous loss‐of‐function variants in the spermine synthase (SMS) gene, resulting in decreased or ...
Elizabeth A. VanSickle +26 more
wiley +1 more source