Results 91 to 100 of about 24,121 (231)

Translational Physiologically Based Pharmacokinetic Modeling to Predict Human Pulmonary Kinetics After Lung Delivery

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 4, Page 796-806, April 2025.
ABSTRACT Predicting human lung exposure with reasonable certainty of orally inhaled drugs based on preclinical studies remains a challenge for drug development. We have developed a comprehensive physiologically based pharmacokinetic (PBPK) framework tailored for the pulmonary pharmacokinetic (PK) behavior in both humans and rats, aiming to bridge the ...
Haini Wen, Muhammad Waqas Sadiq, Lena E. Friberg, Elin M. Svensson   +3 more
wiley   +1 more source

THE EFFECT OF DIFFERENT NEBULIZERS WITH AND WITHOUT INTERMITTENT POSITIVE PRESSURE BREATHING ON THE ABSORPTION AND METABOLISM OF SALBUTAMOL [PDF]

, 1974
Gillian M. Shenfield, M E Evans, James W. Paterson   +2 more
openalex   +1 more source

MOF‐Based Bioelectronic Supercapacitors

Small, Volume 21, Issue 15, April 16, 2025.
This study examines the structural and functional characteristics of MOF‐based bioelectronic supercapacitors, highlighting their excellent conductivity and biocompatibility. Strategies for synthesis and functionalization enhance overall device efficiency. Due to their diverse application potential, these materials are recognized as promising candidates
Begüm Sarac, Seydanur Yücer, Fatih Ciftci   +2 more
wiley   +1 more source

Evaluation of the Effects of Isoprenaline and Salbutamol Aerosols on Airways Obstruction and Pulse Rates of Children with Asthma [PDF]

, 1970
G. Hambleton, E A Shinebourne
openalex   +1 more source

Genotype‐Guided Asthma Treatment Reduces Exacerbations in Children: Meta‐Analysis of Two Randomized Control Trials

Allergy, Volume 80, Issue 4, Page 1006-1014, April 2025.
This study investigates whether ADRB2‐guided treatment improves asthma control and reduces the risk of exacerbations in children with uncontrolled asthma. We conducted an individual participant data meta‐analysis of two randomised controlled trials: PUFFIN and PACT.
Elise M. A. Slob, Susanne J. H. Vijverberg, Tom Ruffles, Lieke C. E. Noij, Jacqueline Biermann, Alwin F. J. Brouwer, Kristel van den Brink, Annette de Bruin‐Kok, Bart E. Van Ewijk, Eric Haarman, Sanne C. Hammer, Simone Hashimoto, Fiona Hogarth, Christina J. Jones, Arvid W. A. Kamps, Elin T. G. Kersten, Ismé de Kleer, Brian J. Lipworth, Roberta Littleford, Marieke Mérelle, Alexander Moeller, Colin N. A. Palmer, Kristina Pilvinyte, Niels W. Rutjes, Ron H. N. van Schaik, Helen E. Smith, Roger Tavendale, Suzanne W. J. Terheggen‐Lagro, Steve Turner, Jos W. R. Twisk, Anja Vaessen‐Verberne, Mariël Verwaal, Tjalling de Vries, Judit Wesseling, Mariëlle W. Pijnenburg, Gerard H. Koppelman, Somnath Mukhopadhyay, Anke H. Maitland‐van der Zee   +37 more
wiley   +1 more source

Use of salbutamol powder in childhood asthma. [PDF]

, 1978
Warren Lenney, Anthony Milner, E J Hiller   +2 more
openalex   +1 more source

Point‐of‐Care Blood Eosinophils to Predict Preschool Wheeze Attacks

Allergy, Volume 80, Issue 4, Page 1038-1046, April 2025.
Absolute and % BEC at baseline are higher in children who had > 1 wheeze attack requiring unscheduled healthcare attendance in follow‐up period. Decision tree model shows children with BEC ≥ 4% and TRACK score < 75 are more likely to have a future attack.
Kushalinii Hillson, Sara Fontanella, Hernani Almeida, Barbara Pavlou, Katariina Lajunen, Samantha Irving, Ilaria Testa, Yvonne Bingham, Karina Mayoral Oritz, Shane Lacbay, Sophie Hay, Mindy Gore, Elizabeth Scotney, Emmanouil Paraskakis, Samatha Sonnappa, Louise Fleming, Andrew Bush, Sejal Saglani   +17 more
wiley   +1 more source

Characterization of beta‐adrenoceptor subtype mediating the metabolic actions of salbutamol. [PDF]

, 1978
Norbert Berend, GE Marlin
openalex   +1 more source

Immunity, Inflammation and Airway Dysfunction in Elite Cross‐Country Skiers and Ice Hockey Players: A Systematic Review

Scandinavian Journal of Medicine &Science in Sports, Volume 35, Issue 4, April 2025.
ABSTRACT Strenuous exercise in elite sports impacts the immune system, leading to high rates of upper respiratory tract infections and airway dysfunction, such as asthma and exercise‐induced bronchoconstriction (EIB). Cross‐country (XC) skiers and ice hockey (IH) players are particularly affected due to their training environments and sports ...
Eva Jaeger, Debbie J. Maurer, Alexandra Wallimann, Walter Kistler, Beat Villiger, Ioana Agache, Marek Jutel, Kari Nadeau, Maia Rukhadze, Matteo Bonini, Oliver J. Price, Cezmi A. Akdis, Michael Villiger   +12 more
wiley   +1 more source

Intravenous treatment with rimiterol and salbutamol in asthma. [PDF]

, 1975
G. E. Marlin, Paul Turner
openalex   +1 more source