Results 101 to 110 of about 49,093 (269)

Assessing Major Organ Dysfunction in Children With Sickle Cell Disease: Protocol for a Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 5, May 2025.
ABSTRACT Background and Aims Sickle cell disease (SCD) is the most common clinically significant genetic disorder affecting about 300,000 newborns globally each year. In Ghana, a prevalence of 1.8% exists among newborns. With increasing life expectancy, assessment of the effect of progressive organ damage on quality of life becomes essential.
Vivian Paintsil, Sandra Kwarteng Owusu, Samuel Blay Nguah, Serwah Bonsu Asafo‐Agyei, Augustina Badu‐Peprah, Lawrence Osei‐Tutu, Christiana Adu‐Takyi, Tony Boakye, Bernice Eklu, Eugenia Osei, Ruth Owusu‐Antwi, George Asafu‐Adjaye Frimpong, Evans Xorse Amuzu, Daniel Ansong   +13 more
wiley   +1 more source

Dynamics of aerosol size during inhalation : Hygroscopic growth of commercial nebulizer formulations [PDF]

, 2014
We thank the Elizabeth Blackwell Institute (EBI) for financial support through the EBI Early Career Research Fellowship awarded to AEH, and the EPSRC for financial support through a Leadership Fellowship awarded to JPR (grant reference EP/G007713/1 ...
Allen E. Haddrell, Asgharian, Berg, Bones, Broday, Carvalho, Chan, Clegg, Clegg, Darragh Murnane, Davies, Davies, Davies, Dennis, Dubus, Ferron, Ferron, Finlay, Finlay, Forbes, Haddrell, Haddrell, Hargreaves, James F. Davies, Johnson, Jonathan P. Reid, Kallstrom, Kim, Krajnik, Kulmala, Kwong, Labiris, Lavorini, Lea Ann Dailey, Martonen, Mccallion, Mitsakou, Morrow, Nerbrink, Prokop, Rachael E.H. Miles, Reid, Reisner, Watts, Xi, Zhou   +45 more
core   +1 more source

Dexamethasone regime and clinical outcomes in children hospitalized with croup: A cohort study

Journal of Hospital Medicine, Volume 20, Issue 5, Page 454-462, May 2025.
Visual Abstract Abstract Background High‐quality trial evidence supports the use of one dose of dexamethasone in the outpatient management of croup; however, there are no inpatient trials, and the optimal treatment regimen for the inpatient management of croup remains uncertain. Significant practice variability exists in the corticosteroid treatment of
David D'Arienzo, Muhammadhasan Nasser, Peter J. Gill, Cornelia M. Borkhoff, Patricia C. Parkin, Sanjay Mahant   +5 more
wiley   +1 more source

Exercise performance after salbutamol inhalation in non-asthmatic, non-athlete individuals: a randomised, controlled, cross-over trial

BMJ Open Sport & Exercise Medicine, 2018
Background Asthma is a frequent diagnosis in competitive sports, and inhaled β2-agonists are commonly used by athletes. Although inhaled β2-agonists do not seem to improve performance in athletes, it has remained uncertain whether they can increase ...
Filip Eckerström, Christian Emil Rex, Marie Maagaard, Sune Rubak, Vibeke Elisabeth Hjortdal, Johan Heiberg   +5 more
doaj   +1 more source

Identifying Ligand Binding Conformations of the β2-Adrenergic Receptor by Using Its Agonists as Computational Probes [PDF]

, 2011
Recently available G-protein coupled receptor (GPCR) structures and biophysical studies suggest that the difference between the effects of various agonists and antagonists cannot be explained by single structures alone, but rather that the conformational
Ashley M. Buckle, B Isin, B Isin, B Isin, Basak Isin, BK Kobilka, BK Kobilka, C Gales, CD Strader, CD Strader, CD Strader, DL Farrens, DM Rosenbaum, DM Rosenbaum, DS Han, E Reiter, FZ Chung, G Liapakis, G Liapakis, G Swaminath, G Swaminath, Guillermina Estiu, GV Paolini, HW Choe, I Bahar, JA Javitch, JC Phillips, JE Olsson, JJ Liu, JP Overington, K Palczewski, K Wieland, KA Reynolds, L Shi, LM Luttrell, LS Barak, M Arakawa, M Azzi, MA Yildirim, MP Bokoch, MS Johnson, O Fritze, Olaf Wiest, P Ghanouni, PG Strange, R Nygaard, R Seifert, RA Friesner, RA Friesner, RO Dror, S Ahuja, S Bhattacharya, S Ludeke, SA Green, SG Rasmussen, SG Rasmussen, SG Rasmussen, T Palanche, TD Romo, U Gether, V Cherezov, X Deupi, X Yao, X Zhang, Zoltán N. Oltvai   +64 more
core   +3 more sources

Pulmonary MRI in Newborns and Children

Journal of Magnetic Resonance Imaging, Volume 61, Issue 5, Page 2094-2115, May 2025.
Lung MRI is an important tool in the assessment and monitoring of pediatric and neonatal lung disorders. MRI can provide both similar and complementary image contrast to computed tomography for imaging the lung macrostructure, and beyond this, a number of techniques have been developed for imaging the key functions of the lungs, namely ventilation ...
Neil J. Stewart, Nara S. Higano, Lena Wucherpfennig, Simon M.F. Triphan, Amy Simmons, Laurie J. Smith, Mark O. Wielpütz, Jason C. Woods, Jim M. Wild   +8 more
wiley   +1 more source

Salbutamol Abuse is Associated with Ventricular Fibrillation

Turkish Journal of Emergency Medicine, 2015
SUMMARY: Salbutamol-induced cardiac complications are well-established. Herein, we describe a case of a 24-year female who was admitted to the emergency department because of a suicide attempt with salbutamol (76 mg).
Emin UYSAL, Suleyman SOLAK, Murat CARUS, Nedim UZUN, Erdem CEVIK   +4 more
doaj  

Comparative study of the bronchodilator efficacy and adverse effects of salbutamol and hyoscine butylbromide in horses with severe asthma

Journal of Veterinary Internal Medicine
Background Salbutamol and hyoscine butylbromide (HBB) are commonly used bronchodilators in horses with severe asthma (SA). Objective To compare the bronchodilation potency, duration, and adverse effects of salbutamol and HBB in SA.
Berta Mozo Vives, Sophie Mainguy‐Seers, Jean‐Pierre Lavoie   +2 more
doaj   +1 more source

The effect of mode of inhaled salbutamol delivery on measures of small airways obstruction in asthma: a comparison of treatment delivered via spacer and nebuliser

New Zealand Medical Student Journal, 2020
Background Conventional clinical respiratory tests tell us little about the small airways of the lung (less than 2 mm in internal diameter). Patients with asthma affecting the small airways may respond differently to inhaled bronchodilator treatment ...
Aqeeda Singh, Jan Cowan, Jack Dummer
doaj  

Outbreak of Enterovirus D68 in Young Children, Brescia, Italy, August to November 2024

Journal of Medical Virology, Volume 97, Issue 5, May 2025.
ABSTRACT Enterovirus D68 (EV‐D68) is responsible for a plethora of clinical manifestations ranging from asymptomatic infections to severe respiratory symptoms and neurological disorders. EV‐D68 was first detected in children with pneumonia in 1962 and, from then, only sporadic cases were reported until 2014, when outbreaks were notified across the ...
Serena Messali, Anna Bertelli, Laura Dotta, Marta Giovanetti, Leonardo Sclavi, Giulia Venneri, Massimo Ciccozzi, Raffaele Badolato, Arnaldo Caruso, Francesca Caccuri   +9 more
wiley   +1 more source