Results 21 to 30 of about 24,121 (231)
Nebulized heparin and salbutamol versus salbutamol alone in acute exacerbations of chronic obstructive pulmonary disease requiring mechanical ventilation: a double-blind randomized controlled trial [PDF]
Korean Journal of Anesthesiology, 2020 Background Nebulized heparin has been effectively used in the management of many pulmonary diseases. However, its effect on mechanically ventilated patients with acute exacerbation chronic obstructive pulmonary disease (AECOPD) has never been studied ...
Tarek Mohamed Ashoor +2 more
doaj +1 more source
Effect of single doses of S-salbutamol, R-salbutamol, racemic salbutamol, and placebo on the airway response to methacholine. [PDF]
Thorax, 1997 Commercially available salbutamol is a racemic mixture consisting of equal amounts of the two enantiomers, R-salbutamol and S-salbutamol, felt to be active and inert, respectively.A double blind, randomised, four way, crossover study was performed in 12 well controlled asthmatic subjects (forced expiratory volume in one second (FEV1) > 70% predicted ...
Donald W. Cockcroft, V A Swystun
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Pharmaceutics, 2020 Recent studies have shown that β2-Adrenoreceptor is a regulator of the a-synuclein gene driving risk of Parkinson’s disease. The β2-AR agonist (R)-salbutamol, eutomer of rac-salbutamol, may hold therapeutic potential for Parkinson’s
Rui Zhang +6 more
doaj +1 more source
Amorphicity and Aerosolization of Soluplus-Based Inhalable Spray Dried Powders
Pharmaceutics, 2022 Soluplus is a polymer that has been explored to prepare nanocomposites for pulmonary drug delivery and is non-toxic. However, its aerosolization attributes when spray-dried have not been investigated.
Bishal Raj Adhikari, Shyamal C. Das
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INVESTIGATION OF SALBUTAMOL TOLERANCE [PDF]
British Journal of Clinical Pharmacology, 1974 A double blind cross‐over study was carried out on patients with reversible airways disease attending an out‐patient clinic. Twenty patients were given either salbutamol (200 μg) or propellant by aerosol for two week periods and in another study twelve patients were given identical tablets containing either salbutamol (4 mg) or placebo for four week ...
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Pharmaceuticals, 2012 Accelerated sinus rhythm is an important side effect of inhaled salbutamol which is especially harmful in patients with chronic obstructive pulmonary disease (COPD) and coronary heart disease (CHD). Cross-over, randomized, open label study design.
Uta C. Hoppe +4 more
doaj +1 more source
Inhaled Salbutamol for the Treatment of Transient Tachypnea of the Newborn [PDF]
International Journal of Medical Arts, 2020 Background: Transient tachypnea of the newborn [TTN] is a common physiologic lung disorder. Stimulation of β-adrenergic receptors could alleviate the condition.
Ahmed Salama +2 more
doaj +1 more source
Mioclonías inducidas por salbutamol [PDF]
Biomédica, 2018 El salbutamol es un agonista adrenérgico β2 ampliamente empleado en pacientes con enfermedades pulmonares obstructivas y restrictivas. Sus principales efectos secundarios son la taquicardia y el temblor. Las mioclonías son contracciones musculares involuntarias, irregulares, bruscas, breves y repentinas, y pueden ser generalizadas, focales o ...
Montoya Giraldo, María Alejandra +4 more
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Drug Testing and Analysis, EarlyView.Oral administration of salbutamol shows enantioselective disposition in human skeletal muscle, favoring the (S)‐enantiomer with higher relative partitioning of the pharmacologically active (R)‐enantiomer in muscle. This is concerning from an anti‐doping point of view because the anabolic properties demonstrated for salbutamol can potentially be ...
Morten Hostrup +5 more
wiley +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2022 Salbutamol was included in the prohibited list of the World Anti‐Doping Agency (WADA) in 2004. Although systemic intake is banned, inhalation for asthma is permitted but with dosage restrictions.
Perrine Courlet +5 more
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