Formulation pre-screening of inhalation powders using computational atom-atom systematic search method [PDF]
, 2014 This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.The synthonic modeling approach provides ...
Collins, Elizabeth +10 more
core +2 more sources
Drug Testing and Analysis, EarlyView.The study provides information about the impact of physiological gastric conditions on the unbeneficial occurrence of nitrosamine drug substance–related impurities (NDSRIs). Both main factors for nitrosation in the form of acidic conditions and the presence of nitrite were adequately chosen for triggering the conversion of drug compounds into NDSRIs ...
Matthias Vogel +5 more
wiley +1 more source
Regular treatment with formoterol and inhaled steroids for chronic asthma: serious adverse events (Review) [PDF]
, 2009 Background Epidemiological evidence has suggested a link between beta2-agonists and increases in asthma mortality. There has been much debate about possible causal links for this association, and whether regular (daily) long-acting beta2-agonists are ...
Cates, CJ, Jaeschke, R, Lasserson, TJ
core +1 more source
Quantitation of Formoterol, Salbutamol, and Salbutamol-4′-O-Sulfate in Human Urine and Serum via UHPLC-MS/MS [PDF]
, 2023 The adrenergic beta-2 agonists formoterol and salbutamol are used for the treatment of asthma and COPD but are also misused in sports competitions. Therefore, they are included in WADA regulations.
Bizjak, Daniel A. +6 more
core +1 more source
European Journal of Heart Failure, EarlyView.The beneficial effects of finerenone in patients with heart failure (HF) and mildly reduced or preserved ejection fraction were consistent, regardless of a history of chronic obstructive pulmonary disease (COPD) status. BMI, body mass index; LVEF, left ventricular ejection fraction; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide.
Jawad H. Butt +16 more
wiley +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2022 Salbutamol was included in the prohibited list of the World Anti‐Doping Agency (WADA) in 2004. Although systemic intake is banned, inhalation for asthma is permitted but with dosage restrictions.
Perrine Courlet +5 more
doaj +1 more source
Switching patients from other inhaled corticosteroid devices to the Easyhaler(®) : historical, matched-cohort study of real-life asthma patients [PDF]
, 2014 Peer reviewedPublisher ...
Gould, Shuna +5 more
core +1 more source
In Situ Gels for Nasal Delivery: Formulation, Characterization and Applications
Macromolecular Materials and Engineering, EarlyView.Drug delivery through the nasal route offers many advantages, but is hampered by a number of challenges, such as the short drug retention time caused by mucociliary clearance. In situ forming gels, which undergo a sol‐to‐gel transition with specific triggers at the site of action, present real opportunities in this field.
Li Qian +2 more
wiley +1 more source
Generic sample preparation combined with high-resolution liquid chromatography- time-of-flight mass spectrometry for unification of urine screening in doping-control laboratories [PDF]
, 2010 A unification of doping-control screening procedures of prohibited small molecule substances—including stimulants, narcotics, steroids, ß2-agonists and diuretics—is highly urgent in order to free resources for new classes such as banned proteins ...
Georgakopoulos, C.G. +4 more
core +3 more sources
Global emergency medicine: A scoping review of the literature from 2023
Academic Emergency Medicine, EarlyView.Abstract Objective The Global Emergency Medicine Literature Review (GEMLR) highlights the highest‐quality research addressing emergency care in resource‐limited settings (ECRLS). This 18th edition reviews global emergency medicine (GEM) literature published during 2023.
Braden J. Hexom +76 more
wiley +1 more source