Results 31 to 40 of about 13,081 (222)

Roles of Hormones in Elevated pH-Mediated Mitigation of Copper Toxicity in Citrus sinensis Revealed by Targeted Metabolome

open access: yesPlants, 2023
The effects of copper (Cu)–pH interactions on the levels of hormones and related metabolites (HRMs) in Citrus sinensis leaves and roots were investigated.
Jiang Zhang   +7 more
doaj   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero   +5 more
wiley   +1 more source

A Symmetric Cogeneration Fuel Cell for Coupled Production of Hydrogen, Ammonia and Formate

open access: yesAdvanced Science, EarlyView.
A symmetric cogeneration fuel cell integrating value‐added chemical synthesis with electricity generation by coupling formaldehyde oxidation with the nitrate reduction was developed. This work highlights the broader potential of symmetric cogeneration fuel cells as a general platform for rational reaction pairing, offering a practical pathway to lower ...
Yingjie Song   +8 more
wiley   +1 more source

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan   +6 more
wiley   +1 more source

COVID-19 IN INFLAMMATORY BOWEL DISEASE: SHOULD WE BE MORE CAREFUL WITH THE USE OF SALICYLATES? [PDF]

open access: yesArquivos de Gastroenterologia
Backgrounds: Fortunately, much has been studied about COVID-19 in patients with inflammatory bowel diseases (IBD). Evidence suggests that these patients do not appear to be at increased risk of severe COVID-19. However, there are still some uncertainties
Mariana Rolim Fernandes MACEDO   +17 more
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

open access: yesAdvanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai   +7 more
wiley   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal   +5 more
wiley   +1 more source

Delay of Cucumber Senescence and Life‐Extending Capabilities on Caenorhabditis elegans With the Postharvest Application of Sorbitol and Methyl Salicylate

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Methyl salicylate and sorbitol were taken as coating agents. Caenorhabditis elegans was taken as an animal model. The coated agents were applied in C. elegans. The life span study in C. elegans proves the authenticity of MS and SL. MS and SL extended the post‐harvest life of cucumber for 14 days.
Chirayu H. Trivedi   +3 more
wiley   +1 more source

News and controversy in inflammatory bowel disease treatment

open access: yesItalian Journal of Medicine, 2013
Background: The treatment of Inflammatory bowel disease comes from many years of esperience, clinical trials and mistakes. Discussion: In patients with active Crohn disease steroids are considerated the first choice, but recently, the introduction of ...
Giulia Straforini   +5 more
doaj   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

open access: yesAdvanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang   +5 more
wiley   +1 more source

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