Results 71 to 80 of about 21,878 (269)

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

Amino acid vectorization of salicylic acid enables efficient activation of NPR1‐dependent defense without phytotoxicity

open access: yesPest Management Science, EarlyView.
Amino acid‐vectorized salicylic acid activates PR1/NPR1‐dependent defenses without phytotoxicity, showing an efficient strategy for controlled delivery and enhanced plant immunity. Abstract BACKGROUND Addressing global food security under rapid population growth and climate change requires sustainable strategies to protect crops from pathogens while ...
Ruth Oussou   +6 more
wiley   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa   +9 more
wiley   +1 more source

"Pharmacology of salicin derivatives in sheep" : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2016
Content removed from thesis due to copyright reasons: Figure 1.20(e). S. viminalis. Retrieved from Valerie J.:http://gardeners-word.blogspot.co.uk/Sheep suffer from pain during various husbandry practices as well as during injury or diseases such as ...
Mathurkar, Shashwati Chandrakant
core  

Shrubs inhibit plant diseases by intercepting light in alpine meadows

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Climate change is disproportionately impacting mountain ecosystems, leading to widespread shrub expansion into alpine meadows. Shrub encroachment alters the albedo, carbon budget and warming rate in alpine grasslands, but it remains challenging to predict how shrub ...
Yimin Zhao   +5 more
wiley   +1 more source

Rheumatic Fever: Natural History and Treatment [PDF]

open access: yes, 1965
Major advances in clinical and laboratory research methods have significantly clarified the identification and natural course of rheumatic fever in the past two ...
Feinstein, Alvan R.
core   +1 more source

Complex multitrophic species interactions and fitness costs: Intricate consequences of jasmonate and salicylate induced plant defences

open access: yesJournal of Animal Ecology, EarlyView.
This study reveals how long‐term activation of jasmonic and salicylic acid signalling reshapes arthropod communities and plant fitness across seasons. By showing that induced defences generate contrasting outcomes and cascading trade‐offs across trophic levels, it challenges the assumption that induced resistance is uniformly beneficial in natural ...
Mônica F. Kersch‐Becker   +6 more
wiley   +1 more source

Natural dairy cow health [PDF]

open access: yes, 2011
guide to keeping your herd healthy with herbs and other natural ...
Groot, Maria   +3 more
core  

Comparative Molecular Insights into Developmental and Behavioral Toxicity Induced by Octocrylene and Ethylhexyl Salicylate Exposure on Zebrafish

open access: yesIntegrative Zoology, EarlyView.
This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu   +5 more
wiley   +1 more source

The use of topical diclofenac in the pain management of osteoarthritis of the knee [PDF]

open access: yes, 2006
Osteoarthritis (OA) is a common complaint that affects millions of people worldwide. As there is no cure for OA, drug treatment is the main form of management.
Banning, M
core  

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