Results 81 to 90 of about 44,928 (253)

Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease [PDF]

, 2001
BACKGROUND: Previous studies have suggested that the use of nonsteroidal antiinflammatory drugs (NSAIDs) may help to prevent Alzheimer's disease. The results, however, are inconsistent.
Breteler, M.M.B. (Monique), Duijn, C.M. (Cornelia) van, Hofman, A. (Albert), Launer, L.J. (Lenore), Ruitenberg, A. (Annemieke), Stijnen, Th. (Theo), Stricker, B.H.Ch. (Bruno), Veld, B.A. in 't   +7 more
core   +1 more source

Microbially Influenced Corrosion in Epoxy‐Ceramic Coated Carbon‐Steel Cooler

Materials and Corrosion, EarlyView.
A significant localization of corrosion attacks up to 1 mm deep were found in coated carbon‐steel cooler. Corrosion products and biofilm were enriched in mixed bacterial community including the genera Sulfuritalea and Methylotenera. Analysis of metabolic markers confirmed their coexistence with sulfate‐reducing bacteria.
Veronika Hlavackova, Petr Koutnik, Klara Liskova, Jiri Cmelik, Jakub Riha, Jan Stoulil, Alena Sevcu   +6 more
wiley   +1 more source

Catabolic pathway acquisition by rhizosphere bacteria readily enables growth with a root exudate component but does not affect root colonization

mBio
Horizontal gene transfer (HGT) is a fundamental evolutionary process that plays a key role in bacterial evolution. The likelihood of a successful transfer event is expected to depend on the precise balance of costs and benefits resulting from pathway ...
Stephan Christel, Alyssa A. Carrell, Leah H. Hochanadel, Manuel I. Villalobos Solis, Paul E. Abraham, Sara S. Jawdy, Julie E. Chaves, Nancy L. Engle, Timkhite-Kulu Berhane, Tao Yao, Jin-Gui Chen, Wellington Muchero, Timothy J. Tschaplinski, Melissa A. Cregger, Joshua K. Michener   +14 more
doaj   +1 more source

AAD-2004, a potent spin trapping molecule and microsomal prostaglandin E synthase-1 inhibitor, shows safety and efficacy in a mouse model of ALS [PDF]

, 2010
While free radicals and inflammation constitute major routes of neuronal injury occurring in neurodegenerative diseases, neither antioxidants nor nonsteroidal anti-inflammatory drugs (NSAIDs) have shown significant efficacy in human clinical trials.
Bok Yun, Byoung Gwag, Doo Im, Jae Lee, Jin Lee, Jin Shin, Joe Springer, Soo Byun, Sun Park, Sun Son, Woong Cho, Yong Lee, Young Lee   +12 more
core   +1 more source

Thiol‐X Chemistry: A Skeleton Key Unlocking Advanced Polymers in Additive Manufacturing

Macromolecular Materials and Engineering, EarlyView.
Additive manufacturing and thiol‐X chemistry form a powerful combination for fabricating a diverse array of advanced polymers to address contemporary engineering applications. Thiol‐X reactions offer versatile polymerization mechanisms, “click” reactivity, functional group tolerance, desirable properties, and compatibility over a broad range of 3D ...
James Anthony Dicks, Chris Woolard
wiley   +1 more source

When alarm bells ring: emergency tinnitus [PDF]

, 2016
OBJECTIVE: The aim of this study is to develop a diagnostic-therapeutic algorithm for those suffering from tinnitus who seek emergency aid. MATERIALS AND METHODS: A literature review has been performed on articles from the last 30 years. RESULTS: It is
Altissimi, Giancarlo, Cianfrone, Giancarlo, Ciofalo, Andrea, Greco, Antonio, Marinelli, C, Mazzei, F, Orlando, Maria Patrizia, Salviati, M, Testugini, C, Turchetta, Rosaria, Vincentiis, M. DE   +10 more
core  

Salicylates increase insulin secretion in healthy obese subjects.

Journal of Clinical Endocrinology and Metabolism, 2008
CONTEXT Conflicting results on the effects of salicylates on glucose tolerance in subjects with normal glucose tolerance or type 2 diabetes have been reported.
J. Fernández-Real, A. López‑Bermejo, A. Ropero, S. Piquer, A. Nadal, J. Bassols, R. Casamitjana, R. Gomis, E. Arnáiz, I. Pérez, W. Ricart   +10 more
semanticscholar   +1 more source

Melt Processing of Cellulose Acetate for Controlled Release Applications – A Review

Macromolecular Materials and Engineering, EarlyView.
This review presents recent developments in the melt‐processing of cellulose acetate (CA). Factors affecting the processability, biodegradability, and mechanical performance of CA are also summarized. Plasticizers, bio‐based polymers (PLA, PBAT & PHBV), and clay nanoparticles are also examined toward enhancing the melt processability and mechanical ...
Thabang N. Mphateng, António Benjamim Mapossa, Teboho Mokhena, Suprakas Sinha Ray, Uttandaraman Sundararaj   +4 more
wiley   +1 more source

The Effect of Salsalate Therapy on Endothelial Function in a Broad Range of Subjects [PDF]

, 2014
Background: Inflammation is fundamental to the development of atherosclerosis. We examined the effect of anti‐inflammatory doses of salicylate on endothelium‐dependent vasodilation, a biomarker of cardiovascular risk, in a broad range of subjects ...
Beckman, Joshua A., Buck, J. Stewart, Copeland‐Halperin, Robert, Kim, Sora, Kinlay, Scott, Nohria, Anju, Redline, Whitney   +6 more
core   +1 more source

The Hsp90β Isoform: An Attractive Target for Drug Development

Medicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury, Terin D'Amico, Brian S. J. Blagg   +2 more
wiley   +1 more source