Results 41 to 50 of about 341,134 (308)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Learning salience amoung [sic] features through contingency in the CEL framework [PDF]
, 1985 Determining which features in an environment are salient given a task, salience assignment, is a central problem in Machine Learning. A related phenomenon, contingency (the conditions under which relative salience among environmental features is acquired)
Granger, R. H., Jr. +1 more
core +1 more source
Examining the Relationships Among Categorization, Stereotype Activation, and Stereotype Application. [PDF]
, 2020 Increased category salience is associated with increased stereotyping. Prior research has not examined the processes that may account for this relationship.
Ma, Debbie S +2 more
core
Salience and default mode network coupling predicts cognition in aging and Parkinson’s disease [PDF]
, 2016 OBJECTIVES: Cognitive impairment is common in Parkinson’s disease (PD). Three neurocognitive networks support efficient cognition: the salience network, the default mode network, and the central executive network.
Cronin-Golomb, Alice +4 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Ecology and Society, 2019 Protected areas and adjacent landscapes are increasingly being viewed as integrated. A more general awareness is emerging of the relevance of collectively managed landscapes for conservation and human well-being.
Lelani M. Mannetti +3 more
doaj +1 more source
Dying to Eat: Terror Management and Attitudes Toward Eating Plants [PDF]
, 2018 Terror management theory posits that the drive for self-preservation and the knowledge of our inevitable death create anxiety in people, which they manage in a variety of ways, including favoring those who are like them and distancing themselves from ...
Lewis, Erika J
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source