Results 171 to 180 of about 116,902 (337)
Advanced Science, EarlyView.By studying the maturation mechanisms of vasopressin (AVP), this manuscript identifies FAM134B‐mediated ER‐phagy as a critical pathway for degrading both aggregated proAVP and the key ERAD component, HRD1. HRD1 induction mitigates proAVP aggregation and support AVP neuron function in the absence of autophagy.
Xuya Pan +16 more
wiley +1 more source
High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection
Advanced Science, EarlyView.Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni +15 more
wiley +1 more source
Object Feature Extraction by Using the Searching Temporal and Feature Salient Technique [PDF]
, 2000 Ching-Liang Su
openalex +1 more source
IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation
Advanced Science, EarlyView.LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu +10 more
wiley +1 more source
Characteristics of 3-phase Salient-pole Synchronous Motor Driven by Thyristor Inverter
, 1972 Sakutaro Nonaka, Jun Oyama
openalex +2 more sources
Measuring, modeling, and decoupling of saturation-induced saliencies in carrier-signal injection-based sensorless AC drives [PDF]
, 2001 Fernando Briz +3 more
openalex +1 more source
Advanced Science, Volume 12, Issue 20, May 29, 2025.Spatially resolved multiomics reveals that high‐copper zones are closely associated with tumor metastasis, immune‐desert phenotypes, and oxidative‐phosphorylation (OXPHOS)‐dependent proliferation. A targeted bacterial nanovesicle delivering copper‐depleting agents effectively reduces tumor copper levels, inhibits OXPHOS‐dependent tumor growth, and ...
Lin Chen +16 more
wiley +1 more source
Phoneme Discretized Saliency Maps for Explainable Detection of AI-Generated Voice [PDF]
arXivIn this paper, we propose Phoneme Discretized Saliency Maps (PDSM), a discretization algorithm for saliency maps that takes advantage of phoneme boundaries for explainable detection of AI-generated voice. We experimentally show with two different Text-to-Speech systems (i.e., Tacotron2 and Fastspeech2) that the proposed algorithm produces saliency maps
arxiv
Advanced Science, Volume 12, Issue 20, May 29, 2025.As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang +10 more
wiley +1 more source