Results 201 to 210 of about 12,627 (258)

Intramolecular Interactions between Folded and Disordered Regions Shape Ubiquilin Structure and Function

open access: yesAdvanced Science, EarlyView.
Ubiquilin (UBQLN), like many other human proteins, contains both well‐folded and disordered regions. Here, we show that intramolecular interactions between disordered regions and folded domains modulate between open and closed topologies of UBQLN proteins, altering their structure and function.
Jessica K. Niblo   +4 more
wiley   +1 more source

Unconventional Hysteretic Charge Filling in Moiré‐Reconstructed Helical Trilayer Graphene

open access: yesAdvanced Science, EarlyView.
In helical trilayer graphene, sequential twisting reconstructs the moiré landscape into periodic domains separated by aperiodic boundaries. Longitudinal transport reveals sweep‐direction‐dependent hysteresis, while the Hall response traces this behavior to hysteretic charge filling at the aperiodic boundaries.
Hangyeol Park   +9 more
wiley   +1 more source

Consistent explainable image quality assessment for medical imaging. [PDF]

open access: yesHealth Inf Sci Syst
Ozer C   +3 more
europepmc   +1 more source

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

open access: yesAdvanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li   +7 more
wiley   +1 more source

Synergistic 3D Porous Architectures and Halogen Redox Chemistry for High‐Energy and High‐Power Microbatteries

open access: yesAdvanced Science, EarlyView.
3D porous Ni scaffolds with PANI cathode, Zn anode, and halogen redox chemistry synergistically enhance on‐chip microbattery performance by improving active material loading, Zn2+ diffusion, and charge‐transfer kinetics. The resulting 3D Zn//I2 microbatteries deliver high areal capacity, high energy and power density, and excellent cycling stability ...
Yijia Zhu   +6 more
wiley   +1 more source

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