Results 111 to 120 of about 2,960,330 (391)
Particulate Matter Exposure Impairs Systemic Microvascular Endothelium-Dependent Dilation [PDF]
, 2004 Acute exposure to airborne pollutants, such as solid particulate matter (PM), increases the risk of cardiovascular dysfunction, but the mechanisms by which PM evokes systemic effects remain to be identified.
Barger, Mark +4 more
core +3 more sources
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
Extent and mechanism of sealing in transected giant axons of squid and earthworms [PDF]
, 1994 Transected axons are often assumed to seal at their cut ends by the formation of continuous membrane barriers that allow for the restoration of function in the axonal stumps.
Ballinger, Martis L. +3 more
core +1 more source
Memorias do Instituto Oswaldo Cruz, 1997 There are several experimental models describing in vivo eosinophil (EO) migration, including ip injection of a large volume of saline (SAL) or Sephadex beads (SEP).
Sandra HP Oliveira +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Behavioural effects of hypersaline exposure on the lobster Homarus gammarus (L) and the crab Cancer pagurus (L) [PDF]
, 2014 There is scarce existing information in the literature regarding the responses of any marine species, especially commercially valuable decapod crustaceans, to hypersalinity.
Elliott, Michael +2 more
core +1 more source
GeoScience Engineering, 2011 Rozvojovými příležitostmi pro post-těžební oblasti by mohly být nové směry podnikání, a rovněž nový přístup k místním přírodní zdrojům. Článek se zabývá charakteristikou solanky vyráběné v podniku odsolení důlních vod „Dębieńsko“ v Czerwionka-Leszczynyna
Tobór-Osadnik Katarzyna +1 more
doaj +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Beilstein Journal of NanotechnologyThe structural and physical properties of microencapsulated iron sucrose and their changes upon dissolution in saline were tested. For the undissolved sample, calcium alginate microcapsules with irregular shapes were registered via scanning electron ...
Sabina Lewińska +7 more
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source