Results 181 to 190 of about 2,960,330 (391)

RCTs: ‘Gold Standard’ for Medical Research Targets Improved Outcomes [PDF]

, 2014
For decades, prospective randomized clinical trials (RCTs) have been the “gold standard” for medical research. These studies randomly assign patients to one of two groups: half receive the standard treatment, and half undergo the experimental approach ...

core   +1 more source

A comparison of albumin and saline for fluid resuscitation in the intensive care unit.

New England Journal of Medicine, 2004
S. Finfer, R. Bellomo, N. Boyce, J. French, J. Myburgh, Robyn Norton   +5 more
semanticscholar   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

XII. On the specific gravity, and temperature of sea waters, in different parts of the ocean, and in particular seas; with some account of their saline contents [PDF]

Alexander Marcet, Alexander Marcet
openalex   +1 more source

La répartition des matières salines dans le lait leurs relations physiques et chimiques avec les autres principes du lait. (Suite et Fin) [PDF]

, 1923
C. PORCHER, A. Chevallier
openalex   +1 more source

Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2017
T. McAlindon, M. Lavalley, W. Harvey, L. Price, J. Driban, Ming Zhang, R. Ward   +6 more
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Concerning the Influence of Saline Media on Fish, etc

, 1884
Sydney Ringer
openalex   +2 more sources

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

FOUR SUCCESSFUL CASES OF TRANSFUSION OF SALINE FLUID. [PDF]

, 1897
Nathan Raw
openalex   +1 more source