Results 111 to 120 of about 786,214 (299)

Effect of sedimentary heterogeneities in the sealing formation on predictive analysis of geological CO₂ storage [PDF]

, 2019
Numerical models of geologic carbon sequestration (GCS) in saline aquifers use multiphase fluid flow-characteristic curves (relative permeability and capillary pressure) to represent the interactions of the non-wetting CO2 and the wetting brine. Relative
Alkan, Amann-Hildenbrand, Amann-Hildenbrand, Anderson, André, Armitage, Bachu, Bastin, Bear, Bennion, Bielicki, Birkholzer, Birkholzer, Bloomfield, Brooks, Burnside, Cameron, Carsel, Class, Deng, Dewhurst, Dewhurst, Doughty, Ducellier, Folk, Handin, Harrington, Hayley Vosper, Hobbs, Howard, IEAGHG, IPCC, John D.O. Williams, Kaldi, Khan, Lenhard, Liu, Michael U. Onoja, Middleton, Miri, Mori, Newell, Nicot, Niemi, Noy, Okwen, Oldenburg, Onoja, Oostrom, Orlic, Orr, Peters, Rutqvist, Rutqvist, Schlumberger, Seedhouse, Seyed M. Shariatipour, Shariatipour, Shariatipour, Shukla, Smith, Standing, Stow, Van Genuchten, Vilarrasa, Williams, Yamamoto, Yang, Yang, Zhang   +69 more
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Feasibility of Nano-Urea and PGPR on Salt Stress Amelioration in Reshmi Amaranth (Amaranthus tricolor): Stress Markers and Enzymatic Response

Horticulturae
The present experiment aimed to examine the impact of nano urea (NU) and plant growth-promoting rhizobacteria (PGPR) on Reshmi amaranth (Amaranthus tricolor) growth under salt stress.
Mohssen Elbagory, Faizah Amer Altihani, Sahar El-Nahrawy, Moustafa Shalaby, Alaa El-Dein Omara, Jogendra Singh, Željko Andabaka, Ivan Širić   +7 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Transcriptome and Physiological Characterization Reveal the Effects of Exogenous MeJA on Turnips Under Salt Stress

Horticulturae
Salt stress severely affects the growth of turnips (Brassica rapa subsp. rapa), leading to a decline in quality and a reduction in yield. Methyl jasmonate is an endogenous plant hormone that plays a role in regulating plant responses to salt stress ...
Chenyang Ma, Zhe Tao, Xingling Yang, Ruiqing Xiao, Kai Jia   +4 more
doaj   +1 more source

Rice Fields Chemical and Physical Properties and the Implications on Breeding Strategie [PDF]

, 2019
Soil related constraints are major limiting factors in crop production in the Sahel. The objective of this study was to assess the properties of farmer's fields soil and irrigation water in Niger and the implications in rice improvement.
Danquah, E., Joseph, B.T.B., Manneh, B., Nartey, E., Ofori, K., Souleymane, O.   +5 more
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source