Results 161 to 170 of about 1,245,388 (394)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Dataset on antioxidant system of non-model halophytes Urochondra setulosa and Dichanthium annulatum in saline environment

open access: yesData in Brief, 2023
The antioxidant potential of halophytes, Dichanthium annulatum and Urochondra setulosa, was examined under the influence of high salinity. These halophytes were grown in lysimeters filled with saline soil and further irrigated with saline water to ...
Anita Mann   +5 more
doaj  

Predicting the Success of Invasive Species in the Great Bay Estuarine Researve [PDF]

open access: yes, 2007
The University of New Hampshire Zoology Department reports on a study designed to continue monitoring the distribution of invasive species in the Great Bay Estuary and to carry out laboratory experiments designed to test the effects of salinity on ...
Dijkstra, Jennifer A., Harris, Larry G.
core   +2 more sources

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

open access: yesMolecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza   +5 more
wiley   +1 more source

Physiological and molecular analysis of salt tolerance in wheat (Triticum aestivum) recombinant inbred lines population (HD2851 × Kharchia 65)

open access: yesThe Indian Journal of Agricultural Sciences
Sodicity is a critical stress that significantly affects the yield and productivity of wheat. This stress can result in a range of physiological, biochemical, and molecular responses in plants, which can hinder their overall health and yield potential ...
AHMED MOHAMMED ISMAIL   +6 more
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

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