Results 141 to 150 of about 292,464 (315)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

The Determination Of Salinity Profile And Nutrition (Nah2po4) Profile In Utilizing Nannochloropsis oculata To Gain Maximum Lipid [PDF]

open access: yes, 2012
The determination of salinity profile and nutrition (NaH2PO4) profile in utilizing Nannochloropsis oculata to gain maximum lipid was investigated. The purpose of carrying out this research is to determine the optimum salinity and the optimum nutrition ...
Elida , Purba,, Kenjiro , Siburian
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Studies on the effects of salinity and heavy metals on the sporophytic & gametophytic generations of Arabidopsis thaliana (L.) heynh [PDF]

open access: yes, 1994
The aim of this research was to study the effects of Salinity & Heavy Metals on the Sporophyte & Gametophyte generations of Arabidopsis thaliana.
Rind Baloch, Ali Hassan
core  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Complex Adaptive System Modelling of River Murray Salinity Policy Options

open access: yes
This paper reports on complex adaptive system (CAS) simulation of the River Murray Basin in Australia to compare capacity of institutional options to maintain functioning of key river system within a "bandwidth" that limits irreversible system state ...
Connor, Jeffery D.
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Salinity tolerance of the tilapias Oreochromis aureus, O. niloticus and an O. mossambicus X O. niloticus hybrid [PDF]

open access: yes
Studies ontogenetic changes in salinity tolerance in tilapias spawned and reared in freshwater using the indices of median lethal salinity, mean survival time and median survival time.
Kuo, C.M., Watanabe, W.O., Huang, M.C.
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

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