Results 141 to 150 of about 350,867 (306)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Complex Adaptive System Modelling of River Murray Salinity Policy Options [PDF]

open access: yes
This paper reports on complex adaptive system (CAS) simulation of the River Murray Basin in Australia to compare capacity of institutional options to maintain functioning of key river system within a "bandwidth" that limits irreversible system state ...
Connor, Jeffery D.
core  

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Development and validation of a DIY profiling float for indirect determination of salinity

open access: yes
Ocean salinity, a measure of salt concentration in seawater, is a key variable influencing water density and controls important processes like mixing and stratification.
Flaim, Caleb
core  

Effect of salinity on growth, proline accumulation and chlorophyll content during vegetative growth, flowering and seed formation of Brassicajuncea L.

open access: yes, 1998
Brassica juncea L (Kraniti) plants were grown in solution cultures having three levels of salinity concentrations (40, 70 and 150 mM w/w)). Higher levels of salinity were achieved by addition of the NaCI, CaCI2 and MgCI2 dissolved in one-fourth strength ...
Gasim, Abdulaziz A.
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Exploring field scale salinity using simulation modeling, example for Rudasht area, Esfahan Province, Iran [PDF]

open access: yes
Salinity / Simulation models / Soil-water-plant relationships / Soil properties / Climate / Irrigated farming / Water quality / Iran / Esfahan Province / Rudasht ...
Akbari, M.   +3 more
core  

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Relative differences in salinity tolerance and genetic expression of salt‐tolerant and sensitive varieties of commercially important Solanaceae crops

open access: yesAgrosystems, Geosciences & Environment
Members of the Solanaceae family, such as tomatoes (Solanum lycopersicum), eggplants (Solanum melongena L.), and peppers (Capsicum chinense L.), are moderately sensitive to salinity, which could limit their production, especially under future water ...
Ray G. Anderson   +5 more
doaj   +1 more source

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