Results 121 to 130 of about 350,867 (306)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Physiological and molecular analysis of salt tolerance in wheat (Triticum aestivum) recombinant inbred lines population (HD2851 × Kharchia 65)

open access: yesThe Indian Journal of Agricultural Sciences
Sodicity is a critical stress that significantly affects the yield and productivity of wheat. This stress can result in a range of physiological, biochemical, and molecular responses in plants, which can hinder their overall health and yield potential ...
AHMED MOHAMMED ISMAIL   +6 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Farmers' ability to cope with salinity and sodicity: Farmers' perceptions, strategies and practices for dealing with salinity and sodicity in their farming systems [PDF]

open access: yes
Soil salinity / Sodic soils / Farming systems / Farmers' attitudes / Soil properties / Soil classification / Soil management / Irrigation water / Water quality / Pakistan / Punjab / Chishtian Sub-Division / Fordwah ...
Kielen, N. C.
core  

The influence of salinity on various life stages of Ruppia tuberosa and implications for its distribution in the Coorong, South Australia. [PDF]

open access: yes, 2014
Despite the obvious decline in the distribution of Ruppia in the Coorong, there have been few extensive studies investigating the factors that control the distribution of this genus.
Kim, Dae Heui
core  

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

An Economic Analysis and Cost Sharing Assessment for Dryland Salinity Management: A case study of the Lower Eyre Peninsula in South Australia [PDF]

open access: yes
Report to Primary Industry and Resources SA. This report has 2 components. Firstly, it discusses issues relating to cost sharing for dryland salinity management.
Stefan Hajkowicz, Mike Young
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Landscape scale regolith variation in hydraulic parameters and its effect on dryland salinity [PDF]

open access: yes, 1997
This paper brings together the results of research into the impact that major faults have on dryland salinity, and the development of revegetation treatments in the wheatbelt of Western Australia.
George, R.   +4 more
core  

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