Results 161 to 170 of about 350,867 (306)

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Water use and salinity in the Murray–Darling Basin: A state-contingent model [PDF]

open access: yes
The supply of water for irrigation is subject to climatic and policy uncertainty. The object of the present paper is to show how the linear and non-linear programming models commonly used in modelling problems such as those arising in the Murray–Darling ...
Mallawaarachchi, Thilak   +2 more
core  

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra   +5 more
wiley   +1 more source

Salinity tolerance of the tilapias Oreochromis aureus, O. niloticus and an O. mossambicus X O. niloticus hybrid [PDF]

open access: yes
Studies ontogenetic changes in salinity tolerance in tilapias spawned and reared in freshwater using the indices of median lethal salinity, mean survival time and median survival time.
Kuo, C.M., Watanabe, W.O., Huang, M.C.
core  

Glycine Betaine-Induced Responses Under Saline Stress in <i>Passiflora edulis</i> f. <i>flavicarpa</i>. [PDF]

open access: yesPlants (Basel)
Oliveira LA   +6 more
europepmc   +1 more source

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