Results 171 to 180 of about 692,226 (362)
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Historical regulation of Victoria's water sector: A case of government failure? [PDF]
This paper analyses the role of government failure in Victoria’s water sector between 1905 and 1984 as evidenced in the rise of in-stream salinity. It will be shown that high levels of salinity can, in part, be attributed to regulatory failure for two ...
Harris, E.
core +1 more source
FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
SURVIVAL AND GROWTH OF CLAM AND OYSTER LARVAE AT DIFFERENT SALINITIES
, 1958 Harry Davis
openalex +2 more sources
FOUR SUCCESSFUL CASES OF TRANSFUSION OF SALINE FLUID. [PDF]
, 1897 Nathan Raw
openalex +1 more source
FEBS Open Bio, EarlyView.Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani +7 more
wiley +1 more source
XII. On the specific gravity, and temperature of sea waters, in different parts of the ocean, and in particular seas; with some account of their saline contents [PDF]
Alexander Marcet, Alexander Marcet
openalex +1 more source
Dryland Salinity: Spatial Impacts and Farmers' Options [PDF]
The salinisation of farmland in Australia is a major natural resource management problem. Over the next 20 years a further 1.1 million hectares of broadacre farmland is predicted to become salt-affected.
Kingwell, Ross S.
core +1 more source
Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice
Aging and Cancer, EarlyView.Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth +7 more
wiley +1 more source