Results 41 to 50 of about 10,682 (261)
Revista Brasileira de Engenharia Agrícola e Ambiental, 2006 El riego complementario con aguas sódicas conduce a procesos dispersivos que deterioran el espacio poroso y con ello otras propiedades relacionadas. Esto podría producirse con bajos a medios niveles de RAS del agua, en suelos gruesos, cuando la illita ...
Mabel Vázquez +2 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Frontiers in Microbiomes, 2023 The impact of salinization on freshwater ecosystems became apparent during the 2022 ecological disaster in the Oder River, located in Poland and Germany, which was caused by salt discharge from mining activities.
Helen Tammert +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
COMPARATIVE QUALITATIVE AND QUANTITATIVE ANALYSIS OF THE TERSKO SULAKSKAY LOWLAND'S AREAS
Вестник Дагестанского государственного технического университета: Технические науки, 2016 Data are obtained in the comparative analysis of cartographic materials on the Tersko-Sulaksky lowland (50-2000 years). In comparison with fifties the increase in extent of salinization of soils and their area more than twice is revealed, reduction of ...
M. E. Kotenko, E. M. Gadjieva
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
EQA, 2009 In the frame of a multidisciplinary project of research on the San Vitale Pinewood ecosystem, north of Ravenna, the Sr isotope study of a soil profile developed on an old coastal dune aiming at detecting the effect of salinization is presented.
Umberto Masi, Francesca Castorina
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source