Results 81 to 90 of about 169,118 (334)

Physiological Comparison of Two Salt-Excluder Hybrid Grapevine Rootstocks under Salinity Reveals Different Adaptation Qualities [PDF]

open access: gold, 2023
Pranavkumar Gajjar   +13 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Hydrochemistry of alluvial aquifer in the Cobra River sub-basin

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental
The regional characteristics of waters from alluvial aquifers are different, since they depend on geology and climate. Also, there may be local variation in the quality of the available water when the water source is superficial (rivers and lakes) or is ...
Alexandre de O. Lima   +5 more
doaj   +1 more source

Water and soil salinity management and Sslt redistribution in irrigation systems [PDF]

open access: yes, 2006
Soil salinity is present in most of the large irrigation schemes over the world under the conjunctive effect of low quality irrigation water, aridity and lack of natural drainage ofsoils and aquifers.
Bouarfa, Sami   +8 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Influence of Groundwater Depth on Salt Migration and Maize Growth in the Typical Irrigation Area

open access: yesAgronomy
Groundwater depth has a significant impact on salinization in irrigated areas. In this study, different groundwater depths were controlled via pit tests and we conducted pit tests with different groundwater depths (DGWs) to investigate the relationship ...
Liping Dai   +8 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Extent of Salt Affected Land in Central Asia: Biosaline Agriculture and Utilization of the Salt-affected Resources [PDF]

open access: yes
The current status and trends of salinization are discussed with waterlogging of marginal land/plant and water resources problems including strategies for development of integrated biosaline crop-livestock agriculture based system on food-feed crops and ...
Igor Massino   +7 more
core  

Modelling Water Flow and Solute Transport for Horticultural and Environmental Management [PDF]

open access: yes, 2002
During the past 10 years, the simulation model SWAP (Soil, Water, Atmosphere, Plant) was developed by the Sub-Department Water Resources of Wageningen University jointly with the Department Water and Environment of Alterra Green World Research.
Dam, J.C., van, Feddes, R.A.
core   +2 more sources

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