Results 11 to 20 of about 85,722 (268)

Dual function of miR-1248 links interferon induction and calcium signaling defects in Sjögren's syndromeResearch in context

open access: yesEBioMedicine, 2019
Background: Sjögren's syndrome (SS) is one of the most common autoimmune disorders leading to exocrine gland dysfunction. Both immune-dependent processes – like Type I Interferon (IFN) signaling and immune-independent processes – such as calcium ...
Shyh-Ing Jang   +5 more
doaj   +1 more source

Organoid Models for Salivary Gland Biology and Regenerative Medicine

open access: yesStem Cells International, 2021
The salivary gland is composed of an elegant epithelial network that secrets saliva and maintains oral homeostasis. While cell lines and animal models furthered our understanding of salivary gland biology, they cannot replicate key aspects of the human ...
Chen Zhao   +5 more
doaj   +1 more source

A case report of ectopic salivary gland tissue in the tongue base

open access: yesRadiology Case Reports, 2023
Ectopic salivary gland tissue is the presence of normal salivary gland tissue developing outside of the major and minor salivary glands. We present a rare, incidental case of lingual ectopic salivary gland tissue in a 52-year-old male with known Birt ...
Jin Kai Soh, MBChB   +1 more
doaj   +1 more source

Targeting the Ca2+ Sensor STIM1 by Exosomal Transfer of Ebv-miR-BART13-3p is Associated with Sjögren's Syndrome

open access: yesEBioMedicine, 2016
Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease that is associated with inflammation and dysfunction of salivary and lacrimal glands. The molecular mechanism(s) underlying this exocrinopathy is not known, although the syndrome has been ...
Alessia Gallo   +7 more
doaj   +1 more source

Possible proteomic biomarkers for the detection of pancreatic cancer in oral fluids

open access: yesScientific Reports, 2020
The 80% mortality rate of pancreatic-cancer (PC) makes early diagnosis a challenge. Oral fluids (OF) may be considered the ultimate body fluid for non-invasive examinations.
O. Deutsch   +11 more
doaj   +1 more source

Histopathology of salivary glands

open access: yesReumatismo, 2018
Salivary gland (SG) biopsy is a technique broadly applied for the diagnosis of primary Sjögren’s syndrome (pSS), lymphoma accompanying SS, sarcoidosis, amyloidosis, and IgG4-related disease The most peculiar feature of pSS on biopsy is focal lymphocytic sialadenitis.
Carubbi, Francesco   +3 more
openaire   +5 more sources

Salivary gland involvement in granulomatosis with polyangiitis: Case report and review of literature

open access: yesIndian Journal of Rheumatology, 2023
We present a case of granulomatosis with polyangiitis (GPA) presenting with salivary gland enlargement and right parotid abscess, left-sided facial palsy, Lacrimal Gland, extraocular muscle involvement and rapidly progressive necrotizing keratitis ...
Kunal Chandwar   +3 more
doaj   +1 more source

Feline minor salivary gland adenocarcinoma: retrospective case series and literature review

open access: yesJournal of Feline Medicine and Surgery, 2023
Case series summary Salivary gland adenocarcinoma, of major or minor salivary gland origin, is an uncommon tumor in cats. This article describes the clinical features, morbidity and survival rates of four cats with salivary gland adenocarcinoma arising ...
Monica Morgado Laureano   +3 more
doaj   +1 more source

SALIVARY GLAND TUMOURS; FREQUENCY OF SALIVARY GLAND TUMOURS

open access: yesTHE PROFESSIONAL MEDICAL JOURNAL, 2017
Objectives: The objective of the study was to find the frequency of salivarygland tumours. Study Design: A descriptive study. Period: 1st Jan 2008 to 31st Dec 2010 (of 3years duration). Setting: ENT department Khyber Teaching Hospital and Surgical departmentHayatabad Medical Complex, Peshawar.
Arifullah -   +3 more
openaire   +2 more sources

Salivary gland organoid culture maintains distinct glandular properties of murine and human major salivary glands

open access: yesNature Communications, 2022
Salivary glands that produce and secrete saliva, which is essential for lubrication, digestion, immunity, and oral homeostasis, consist of diverse cells. The long-term maintenance of diverse salivary gland cells in organoids remains problematic. Here, we
Yeo-Jun Yoon   +12 more
doaj   +1 more source

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