Results 191 to 200 of about 181,485 (338)

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert   +3 more
wiley   +1 more source

Limited association between HRR gene alterations and HRD in molecular tumor board cancer samples: Who should be tested for HRD?

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Currently, no published data on homologous recombination deficiency (HRD) testing in the setting of molecular tumor boards exist. This study in a cohort of 237 patients encompassing 24 different tumor entities assessed by a molecular tumor board shows that inactivating alterations of BRCA1/2 are not always associated with an elevated ...
Christoph Schubart   +26 more
wiley   +1 more source

Epithelial salivary gland neoplasms in pediatric patients: A comprehensive review. [PDF]

open access: yesMed Oral Patol Oral Cir Bucal
Pérez-de-Oliveira ME   +2 more
europepmc   +1 more source

A promising frontier of circulating messenger RNA in liquid biopsy: From mechanisms to clinical applications

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li   +7 more
wiley   +1 more source

Potassium Iodide Induces Apoptosis in Salivary Gland Cancer Cells. [PDF]

open access: yesInt J Mol Sci
Skrypnyk M   +13 more
europepmc   +1 more source

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