Results 101 to 110 of about 1,699 (253)

TP53 mutations orchestrate partial EMT states in oral squamous cell carcinoma: spatially resolved and in vitro preliminary insights into tumour plasticity

The Journal of Pathology, EarlyView.
Abstract TP53 is the most frequently mutated gene in oral squamous cell carcinoma (OSCC); however, its role in promoting epithelial–mesenchymal transition (EMT) and tumour progression remains unclear, particularly within the context of intra‐tumour heterogeneity.
Rana Alaaeldin Ibrahim, Hong Wan, Raju Kumar, Muy‐Teck Teh, Angray Kang, Emma Bailey, Hannah Cottom, Adrian Biddle, Inês Sequeira, Farida Fortune   +9 more
wiley   +1 more source

Epidemiological drivers of turnip yellows virus and its vector Myzus persicae in Australian canola (Brassica napus) systems: a 3‐year study of commercial crops and noncrop vegetation

Pest Management Science, EarlyView.
A 3‐year study across southern Australia aimed to characterize drivers of infection in the Myzus persicae–turnip yellows virus–Brassica napus pathosystem. Identification of key reservoir hosts and the strong association between earlier sowing and increased disease incidence highlight opportunities for targeted weed management, strategic sowing ...
Samantha E Edley, Owain R Edwards, Benjamin S Congdon, John G Black, Marielle Babineau, Anthony R van Rooyen, Alex Slavenko, Roger AC Jones, Andrew R Weeks, Paul A Umina   +9 more
wiley   +1 more source

Nature‐Inspired Histidine and Guanidine Modification of Magnetic Nanoparticles for Urinary DNA Liquid Biopsy

Small Methods, EarlyView.
Nature‐inspired bi‐functionalized magnetic nanoparticles are engineered for the rapid, non‐invasive extraction of cell‐free DNA from unprocessed urine for liquid biopsy. These cationic particles leverage electrostatic interactions to outperform conventional kits, enhancing the recovery of short DNA fragments while maintaining DNA integrity.
Dina Haddad, Ishtiaq Ahmed, Manthos Pitoulias, Richard Mair, Ljiljana Fruk   +4 more
wiley   +1 more source

Maternal Lead Exposure Induces Glandular Alterations in the Salivary Glands of Rat Male Offspring

Environmental Toxicology, EarlyView.
ABSTRACT Lead (Pb) is a widely distributed environmental pollutant that is highly noxious due to its toxicokinetic characteristics. Pb exposure can damage vital organ systems, including the central nervous and stomatognathic systems. As salivary glands play an important role in oral homeostasis, this study aimed to investigate the effects of maternal ...
Rayssa Maitê Farias Nazário, Deiweson Souza‐Monteiro, Walessa Alana Bragança Aragão, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Raquel Fernanda Gerlach, Antônio Hernandes Chaves‐Neto, Michael Aschner, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Patología quirúrgica de glándulas salivales: Reporte de 79 casos

Revista Cubana de Estomatología, 1999
Se realiza una revisión actualizada de la patología quirúrgica de las glándulas salivales mayores y se presentan los resultados obtenidos en 7 años de experiencia, comprendidos de enero de 1990 a diciembre de 1996 en 79 pacientes portadores de esta ...
Enrique Pérez Abreus, Nurelys González Domínguez   +1 more
doaj  

Extramedullary Plasmacytoma of Base of Tongue: A Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Identifying extramedullary plasmacytoma originating from the base‐of‐tongue, in order to evaluate its prevalence, characteristics, management, and treatment within the broader spectrum of head and neck extramedullary plasmacytoma.
Ori Cohen Michael, Ameen Biadsee, Firas Kassem, Matan Katz, Osnat Jarchowsky‐Dolberg, Benny Nageris, Tomer Boldes   +6 more
wiley   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

Insect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li, Jin Cheng, Ya‐Ming Zou, Quan‐Chao Liu, Ding Zhu, Ce‐Jie Lan   +5 more
wiley   +1 more source

Chronic Submandibular Sialadenitis: A Case Report. [PDF]

Cureus
Gowda Venkatesha RR, Ganesh V, Rajaram Mohan K, Fenn SM, Rajalingam S.   +4 more
europepmc   +1 more source

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

Insect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn, Vicky L. Tolmay, Marlon‐Schylor Luke le Roux, Lintle Mohase, Mpho S. Mafa, Vittorio F. Nicolis, Eduard Venter, Nicolaas Francois Visser Burger, Anna‐Maria Botha   +8 more
wiley   +1 more source