Results 21 to 30 of about 43,636 (257)

Sci-Seq of Human Fetal Salivary Tissue Introduces Human Transcriptional Paradigms and a Novel Cell Population

Frontiers in Dental Medicine, 2022
Multiple pathologies and non-pathological factors can disrupt the function of the non-regenerative human salivary gland including cancer and cancer therapeutics, autoimmune diseases, infections, pharmaceutical side effects, and traumatic injury.
Devon Duron Ehnes, Devon Duron Ehnes, Ammar Alghadeer, Ammar Alghadeer, Ammar Alghadeer, Sesha Hanson-Drury, Sesha Hanson-Drury, Sesha Hanson-Drury, Yan Ting Zhao, Yan Ting Zhao, Yan Ting Zhao, Gwen Tilmes, Julie Mathieu, Julie Mathieu, Hannele Ruohola-Baker, Hannele Ruohola-Baker, Hannele Ruohola-Baker, Hannele Ruohola-Baker   +17 more
doaj   +1 more source

Epidemiological and histopathological patterns of malignant salivary gland tumors in the Sudanese population

Saudi Dental Journal
Background: Malignant salivary gland tumors are rare. However, their morphological overlap and difficulty to differentiate benign from malignant makes diagnosing such diseases a challenging task.
Yassmin Abdalla Mustafa Mohamed, Hagir A. Mahmoud, Fatima Abdalmunim AbdElrahman Eltahir, Abeer Hemedan Mohammed Ahmed, Yousif Osman Yousif   +4 more
doaj   +1 more source

Neurofibromin expression by normal salivary glands

Head & Face Medicine, 2021
Introduction Neurofibromin, a protein encoded by the NF1 gene, is mutated in neurofibromatosis 1, one of the most common genetic diseases. Oral manifestations are common and a high prevalence of hyposalivation was recently described in individuals with ...
Eloá Borges Luna, Pâmella Pinho Montovani, Rafaela Elvira Rozza-de-Menezes, Karin Soares Cunha   +3 more
doaj   +1 more source

Sodium nitrate protects against metabolic syndrome by sialin-mediated macrophage rebalance

Signal Transduction and Targeted Therapy
Metabolic syndrome, characterized by metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes mellitus (T2DM), poses a significant threat to patients’ health worldwide; however, efficient treatment is currently unavailable ...
Shaorong Li, Yaning Wang, Zihan Zhang, Haozhe Xu, Songyue Wu, Hua Jin, Xiaotong Han, Ying Liu, Xin Wen, Yi Wu, Zhongtao Zhang, Lei Hu, Liang Hu, Chunmei Zhang, Jinsong Wang, Renhong Yan, Mo Chen, Guozhi Xiao, Guangyong Sun, Dong Zhang, Songlin Wang   +20 more
doaj   +1 more source

Imaging in major salivary gland diseases

Reumatismo, 2001
Most of the salivary glands diseases are characterized only by a few distinct clinical patterns. Medical history and clinical examination are still considered of great relevance.
C. Botsios, P. Sfriso, C. Grava, P. Ostuni, M. Andretta, A. Tregnaghi, P. Zucchetta, PF. Gambari   +7 more
doaj   +1 more source

ULTRASONOGRAPHIC SALIVARY GLAND RESPONSE TO RITUXIMAB IN SECONDARY SJÖ GREN’S SYNDROME [PDF]

Romanian Journal of Rheumatology, 2018
B cell hyper-reactivity implied in the pathogenesis of Sjö gren’s syndrome (SS) justifies the therapy that involves B cell depletion. Ultrasound of salivary glands demonstrated alterations during disease progression. Objective.
Vasilia Iorgoveanu, Madalina Gheorghe, Violeta Bojinca, Cosmin Constantinescu, Andra Balanescu, Violeta Vlad, Florian Berghea, Laura Groseanu, Maria Magdalena Negru, Mihai Abobului, Daniela Opris-Belinski, Ruxandra Ionescu   +11 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nitrate Enhances Gastric Mucosa Defense and Repair Process in Ethanol‐Induced Gastric Ulcer Rats via the Notch–Tff2 Pathway

MedComm
Gastric mucosal integrity is essential for maintaining systemic homeostasis, serving as the primary defense against external insults. Ethanol ingestion is a major clinical cause of gastric mucosal injury, yet effective prevention or treatment remains ...
Ying Liu, Xin Wen, Yuxuan Lin, Chunmei Zhang, Jinsong Wang, Guangyong Sun, Dong Zhang, Renhong Yan, Mo Chen, Songlin Wang, Shaorong Li   +10 more
doaj   +1 more source

Senescence and fibrosis in salivary gland aging and disease

Journal of Oral Biology and Craniofacial Research
Salivary gland hypofunction is highly prevalent in aged and diseased individuals leading to significant discomfort and morbidity. One factor that contributes to salivary gland hypofunction is cellular aging, or senescence.
Deirdre A. Nelson, Isabella Kazanjian, J. Andres Melendez, Melinda Larsen   +3 more
doaj   +1 more source

Chronic sclerosing sialadenitis (Küttner's tumor) of the submandibular salivary gland: Our experience of one case report

Clinical Case Reports, 2019
Surgical excision of the submandibular salivary gland in patients with chronic sclerosing sialadenitis can be complicated because of hyalinosis of the surrounding soft tissues.
Anna Poghosyan, Martin Misakyan, Ani Sargsyan, Parandzem Khachatryan, Gayane Hakobyan   +4 more
doaj   +1 more source