PLAG1, SOX10, and Myb Expression in Benign and Malignant Salivary Gland Neoplasms [PDF]
Journal of Pathology and Translational Medicine, 2019 Background Recent findings in molecular pathology suggest that genetic translocation and/or overexpression of oncoproteins is important in salivary gland tumorigenesis and diagnosis.
Ji Hyun Lee +8 more
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Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing. [PDF]
Dis Model Mech, 2018 Restricted availability of cell and animal models is a rate-limiting step for investigation of salivary gland neoplasm pathophysiology and therapeutic response.
Alamri AM +10 more
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Review of salivary gland neoplasms. [PDF]
ISRN Otolaryngol, 2012 Salivary gland tumours most often present as painless enlarging masses. Most are located in the parotid glands and most are benign. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours. Investigations such as fine needle aspiration cytology and MRI scans provide some useful information, but ...
To VS, Chan JY, Tsang RK, Wei WI.
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Expression of FOXI1 and POU2F3 varies among different salivary gland neoplasms and is higher in Warthin tumor [PDF]
Discover OncologyPurpose Salivary gland tumors are histologically diverse. Ionocytes and tuft cells, rare epithelial cells found in normal salivary glands, might be associated with salivary tumors.
Masahito Hoki +9 more
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Indian J Med Res, 2018 OCT angiography and have provided the evidence for paracentral acute middle maculopathy. The chapter on macular telangiectasia discusses the superiority of OCT angiography over other imaging techniques including FA and autofluorescence in this disease ...
Kamath A.
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Evaluation of PAX2 and PAX8 expression in salivary gland neoplasms. [PDF]
Head Neck Pathol, 2015 Butler RT +3 more
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Distinct histone H3 modification profiles correlate with aggressive characteristics of salivary gland neoplasms. [PDF]
Sci Rep, 2022 Post-translational modification of histones is the crucial event that affect many tumor-specific traits. A diverse type of histone modifications had been reported in different cancers with prognostic implications.
Lam-Ubol A, Phattarataratip E.
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An Overview on the Histogenesis and Morphogenesis of Salivary Gland Neoplasms and Evolving Diagnostic Approaches. [PDF]
Cancers (Basel), 2021 Simple Summary Diagnosing salivary gland neoplasms (SGN) remain a challenge, given their underlying biological nature and overlapping features. Evolving techniques in molecular pathology have uncovered genetic mutations resulting in these tumors.
Iyer J +8 more
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Expanding the histological spectrum of salivary gland neoplasms with HMGA2::WIF1 fusion emphasising their malignant potential: a report of eight cases. [PDF]
Histopathology, 2023 Recently, HMGA2::WIF1 fusion has been reported in pleomorphic adenoma (PAs) originating from the parotid gland with a characteristic canalicular adenoma (CAA)‐like pattern.
Katabi N +6 more
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Expanding the clinicopathological spectrum of TGFBR3-PLAG1 rearranged salivary gland neoplasms with myoepithelial differentiation including evidence of high-grade transformation. [PDF]
Genes Chromosomes Cancer, 2022 PLAG1 rearrangements have been described as a molecular hallmark of salivary gland pleomorphic adenoma (PA), carcinoma ex pleomorphic adenoma (CEPA), and myoepithelial carcinoma (MECA).
Rupp NJ +7 more
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