A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Correlation of Salivary Gland FNA Reporting Using the Modified Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) and Intraoperative Frozen Section Evaluation with Final Histopathology Report for Major Salivary Gland Neoplasms. [PDF]
Thiagarajan S, Sathe P, Bal M, Patil A.
europepmc +1 more source
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
TANC1::HTRA1 fusion in schwannomas
Brain Pathology, EarlyView.
Ilay Caliskan +3 more
wiley +1 more source
Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin +2 more
wiley +1 more source
Targeting HER2/neu Oncogene Overexpression With Ado-Trastuzumab Emtansine in the Treatment of Metastatic Salivary Gland Neoplasms: A Single-Institution Experience. [PDF]
Swed BL, Cohen RB, Aggarwal C.
europepmc +1 more source
Basement membrane (BM) homeostasis relies on a balance between integrity, controlled remodelling and pathological degradation. Increased protease expression beneath the BM, along with reduced levels of endogenous protease inhibitors, drives the transition from a continuous, protective barrier to a discontinuous interface.
Clara Legendre +2 more
wiley +1 more source
Clear cell changes in salivary gland neoplasms: A 20-year retrospective study. [PDF]
Woods T +4 more
europepmc +1 more source
Staging in Gerodontology: A Framework
ABSTRACT Introduction Comprehensively, systematically and reproducibly assessing and describing the (oral) health status and care needs of older adults is challenging. We aimed to provide a framework for evaluating and reporting older adults' oral health, capturing general and oral function and disease, as well as oral, systemic and socio‐economic ...
Falk Schwendicke +27 more
wiley +1 more source
Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing. [PDF]
Alamri AM +10 more
europepmc +1 more source

