Results 211 to 220 of about 154,087 (288)

Prognostic Significance of the Modified Glasgow Prognostic Score in Patients With Stage IV Melanoma Receiving Immune Checkpoint Inhibitors: A Single‐Center Retrospective Study

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for malignant melanoma (MM). However, given variable response rates and potential toxicities, identifying robust biomarkers is crucial. We investigated whether the modified Glasgow Prognostic Score (mGPS) predicts treatment efficacy and toxicity in Asian patients with
Ken Horisaki   +4 more
wiley   +1 more source

Species‐specific scents, targeted enemies: Volatile cues mediate predator attraction in willows

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Plants produce volatile organic compounds (VOCs) in response to herbivory. Such signals mediate plant interactions with herbivores and their natural enemies. Different herbivores can elicit distinct responses in plants, influencing predator attraction.
Priscila Mezzomo   +9 more
wiley   +1 more source

Germ Panic and Chalice Hygiene in the Church of England, c.1895–1930

open access: yesJournal of Religious History, EarlyView.
The late‐Victorian medical revolution in bacteriology, and growing public awareness of hygienic standards and the danger of disease infection from germs, created alarm about the traditional Christian practice of drinking from a common cup at Holy Communion.
Andrew Atherstone
wiley   +1 more source

[<sup>225</sup>Ac]Ac-PSMA I&T: A Preclinical Investigation on the Fate of Decay Nuclides and Their Influence on Dosimetry of Salivary Glands and Kidneys. [PDF]

open access: yesJ Nucl Med
Wurzer A   +13 more
europepmc   +1 more source

From Tobacco to Ultraprocessed Food: How Industry Engineering Fuels the Epidemic of Preventable Disease

open access: yesThe Milbank Quarterly, EarlyView.
Policy Points Ultraprocessed foods (UPFs) are engineered to heighten reward and accelerate delivery of reinforcing ingredients, driving compulsive consumption and disrupting appetite regulation. This is a growing challenge for health policy. UPFs share key engineering strategies adopted from the tobacco industry, such as dose optimization and hedonic ...
ASHLEY N. GEARHARDT   +2 more
wiley   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

open access: yesInsect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li   +5 more
wiley   +1 more source

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