Results 141 to 150 of about 6,750,036 (340)

BZW1 Drives Immune Evasion in Lung Adenocarcinoma via Ferroptosis Suppression

Advanced Science, EarlyView.
BZW1 attenuates ferroptosis by competitively binding NCOA4 and suppress ferrtinophagy‐mediated iron release. The depletion of BZW1 triggers lipid peroxidation through iron homeostasis. Extracellularly, BZW1 attenuates immunogenic cell death and reinvigorates cytotoxic T‐cell responses.
Linyao Zhao, Yue Peng, Qing Liang, Shi Liu, Yang Li, Lei Ma, Menghan Hu, Sujuan Zheng, Zhihua Liu, Shugeng Gao   +9 more
wiley   +1 more source

Identification of Immmunogenic Salivary Proteins of Anopheles vagus based on Mass Spectrometry Analysis

Jurnal Ilmu Dasar, 2017
Malaria has been prevalent for a long time in tropical developing regions causing great morbidity and mortality. Among the malaria vectors, Anopheles vagus has been known as secondary malaria vector in East Java.
Dwi Esti Febriyantiningsih, Kartika Senjarini, Rike Oktarianti   +2 more
doaj   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source

Novel Molecules for Intra-Oral Delivery of Antimicrobials to Prevent and Treat Oral Infectious Diseases [PDF]

, 2008
New molecules were designed for efficient intra-oral delivery of antimicrobials to prevent and treat oral infection. The salivary statherin fragment, which has high affinity for the tooth enamel, was used as a carrier peptide. This was linked through the
Dentino, Andrew R., Raj, Periathamby A., Rajkumar, Latha   +2 more
core   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

How surface electronegativity and calcium release in enamel mediate the adsorption and lubrication of salivary proteins: The role of interfacial water

Friction
This study investigated the effect of surface electronegativity and calcium release from human enamel on the adsorption and lubrication of salivary proteins from the perspective of interfacial water using three model substrates: calcium-releasing ...
Yue Tang, Lei Lei, Hujun Wang, Haonan Qiu, Jing Zheng, Zhongrong Zhou   +5 more
doaj   +1 more source

Salivary Proteins, Enzymes and Immune Factors Associated With Early Childhood Caries: A Narrative Review

Journal of Pediatrics Review, 2022
Background: Early Childhood Caries (ECC) has many etiologies such as families’ socioeconomic status, parents’ education and awareness, prolonged and improper bottle or breastfeeding, consuming sweet foods and high-sugar diets, brushing techniques ...
Negareh Salehabadi, Aaryousha Moallem Savasari, Azam Nahvi   +2 more
doaj  

Comprehensive Analysis of the Global Protein Changes That Occur During Salivary Gland Degeneration in Female Ixodid Ticks Haemaphysalis longicornis

Frontiers in Physiology, 2019
Ticks are notorious blood-sucking arthropods that can spread a variety of pathogens and cause great harm to the health of humans, wildlife and domestic animals.
Hui Wang, Xiaoli Zhang, Xiao Wang, Baowen Zhang, Minjing Wang, Xiaolong Yang, Xuying Han, Rui Wang, Shuguang Ren, Yuhong Hu, Jingze Liu   +10 more
doaj   +1 more source

Neuronal in vitro impact of Amblyommaamericanumsalivary glands extracts [PDF]

, 2018
When a tick feeds off a host, the salivary glands of the tick excrete saliva to assist the tick in feeding (1). The reason saliva assists the tick in consuming its blood meal is due to its immunosuppressive, anti-inflammatory, and anti-coagulant ...
Leierer, Madi, Londono-Renteria, Berlin, Maldonado, Paulina, Montenegro-Cadena, Lidia   +3 more
core  

Canine Antibodies against Salivary Recombinant Proteins of Phlebotomus perniciosus: A Longitudinal Study in an Endemic Focus of Canine Leishmaniasis

PLoS Neglected Tropical Diseases, 2015
Background Phlebotomine sand flies are vectors of Leishmania parasites. During blood feeding, sand flies deposit into the host skin immunogenic salivary proteins which elicit specific antibody responses. These anti-saliva antibodies enable an estimate of
T. Košťálová, T. Lestinova, P. Sumova, M. Vlková, I. Rohousova, E. Berriatua, G. Oliva, E. Fiorentino, A. Scalone, M. Gramiccia, L. Gradoni, P. Volf   +11 more
semanticscholar   +1 more source