Results 211 to 220 of about 1,700,137 (238)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Antibodies to <i>Aedes aegypti</i> D7L salivary proteins as a new serological tool to estimate human exposure to <i>Aedes</i> mosquitoes. [PDF]

Front Immunol
Chea S, Willen L, Nhek S, Ly P, Tang K, Oristian J, Salas-Carrillo R, Ponce A, Leon PCV, Kong D, Ly S, Sath R, Lon C, Leang R, Huy R, Yek C, Valenzuela JG, Calvo E, Manning JE, Oliveira F.   +19 more
europepmc   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal, Katherine A. Dudley, Stacey Sullivan, Kate T. Brizzi, Katherine M. Burke, Sydney Hall, Kiersten Pease, Joshua N. Goldstein, James D. Berry, Doreen T. Ho   +9 more
wiley   +1 more source

Targeting UDP‐Bta06664 in Bemisia tabaci: A novel strategy to reduce tomato yellow leaf curl virus transmission by impairing insect vector feeding

New Plant Protection, EarlyView.
Tomato yellow leaf curl virus upregulates the Bemisia tabaci UDP‐glycosyltransferase gene UDP‐Bta06664. RNA interference (RNAi) silencing of this gene disrupts phloem feeding—delaying E1 and shortening E2—and reduces both virus acquisition and inoculation, highlighting its potential as an RNAi target.
Zeyu Wan, Liping Huang, Zhanhong Zhang, Xuguo Zhou, Yong Liu, Xiaobin Shi   +5 more
wiley   +1 more source

Bioarcheological Insights From Fragmented Remains: Using Dental Health to Understand the Punic Necropolis of Monte Luna

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT To investigate oral health in the fragmented human remains from the Punic necropolis of Monte Luna, Sardinia, and evaluate what dental pathologies reveal about lifeways and diet. Human remains from 227 individuals recovered from 70 tombs were analyzed, including 21 females, 16 males (> 15 years), and 59 non‐adults (1–15 years).
Rossella Paba, Anna Willis, Kate Domett
wiley   +1 more source

CHARGE Syndrome: What an Otolaryngologist Should Know—A Systematic Review and Meta‐Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To synthesize the prevalence of otolaryngologic manifestations in CHARGE syndrome (CS) to support otolaryngologists in delivering comprehensive management. Data Sources PubMed/MEDLINE, Embase, and Google Scholar were searched for English‐ and French‐language studies published from January 1980 through January 2025.
Camille Caron, Massil Badji, Camille Prigent, Alix Pincivy, Erika Mercier, Mathieu Bergeron   +5 more
wiley   +1 more source

Effect of A Fluoride Toothpaste Containing Enzymes and Salivary Proteins on Periodontal Pathogens in Subjects with Black Stain: A Pilot Study. [PDF]

Eur J Dent
Carelli M, Zatochna I, Sandri A, Burlacchini G, Rosa A, Baccini F, Signoretto C.   +6 more
europepmc   +1 more source

Enterovirus infections in children

Pediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen, Lingyun Guo, Xiaobo Lei, Linqing Zhao, Mingyan Hei, Jun Shen, Ju Yin, Fei Li, Jikui Deng, Gang Liu, Yong Zhang, Zhengde Xie   +11 more
wiley   +1 more source

Epidemiological drivers of turnip yellows virus and its vector Myzus persicae in Australian canola (Brassica napus) systems: a 3‐year study of commercial crops and noncrop vegetation

Pest Management Science, EarlyView.
A 3‐year study across southern Australia aimed to characterize drivers of infection in the Myzus persicae–turnip yellows virus–Brassica napus pathosystem. Identification of key reservoir hosts and the strong association between earlier sowing and increased disease incidence highlight opportunities for targeted weed management, strategic sowing ...
Samantha E Edley, Owain R Edwards, Benjamin S Congdon, John G Black, Marielle Babineau, Anthony R van Rooyen, Alex Slavenko, Roger AC Jones, Andrew R Weeks, Paul A Umina   +9 more
wiley   +1 more source

Long‐term impact of exposure to Royal Guard, a pyriproxyfen‐based bed net, on pyrethroid‐resistant malaria vectors from Cameroon using DNA‐based metabolic resistance markers

Pest Management Science, Volume 81, Issue 4, Page 2165-2180, April 2025.
We used recently detected P450 DNA‐based markers of pyrethroid resistance in both Anopheles funestus and Anopheles gambiae to demonstrate that although pyrethroid‐resistant mosquitoes have higher ability to survive and live longer after exposure to Royal Guard, this net significantly affects their lifespan, blood feeding ability and interestingly ...
Emilie S Ngongang‐Yipmo, Magellan Tchouakui, Benjamin D Menze, Riccado F Tiomela, Derrick Fofie, Vanessa B Ngannang‐Fezeu, Jean L Mugenzi, Flobert Njiokou, Charles S Wondji   +8 more
wiley   +1 more source