Results 61 to 70 of about 1,700,137 (238)

Anopheles gambiae salivary protein expression modulated by wild Plasmodium falciparum infection: highlighting of new antigenic peptides as candidates of An. gambiae bites

Parasites & Vectors, 2014
Background Malaria is the major parasitic disease worldwide caused by Plasmodium infection. The objective of integrated malaria control programs is to decrease malaria transmission, which needs specific tools to be accurately assessed. In areas where the
Alexandra Marie, Philippe Holzmuller, Majoline T Tchioffo, Marie Rossignol, Edith Demettre, Martial Seveno, Vincent Corbel, Parfait Awono-Ambéné, Isabelle Morlais, Franck Remoue, Sylvie Cornelie   +10 more
doaj   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Draft genome sequences of Hirudo medicinalis and salivary transcriptome of three closely related medicinal leeches

BMC Genomics, 2020
Background Salivary cell secretion (SCS) plays a critical role in blood feeding by medicinal leeches, making them of use for certain medical purposes even today.
Vladislav V. Babenko, Oleg V. Podgorny, Valentin A. Manuvera, Artem S. Kasianov, Alexander I. Manolov, Ekaterina N. Grafskaia, Dmitriy A. Shirokov, Alexey S. Kurdyumov, Dmitriy V. Vinogradov, Anastasia S. Nikitina, Sergey I. Kovalchuk, Nickolay A. Anikanov, Ivan O. Butenko, Olga V. Pobeguts, Daria S. Matyushkina, Daria V. Rakitina, Elena S. Kostryukova, Victor G. Zgoda, Isolda P. Baskova, Vladimir M. Trukhan, Mikhail S. Gelfand, Vadim M. Govorun, Helgi B. Schiöth, Vassili N. Lazarev   +23 more
doaj   +1 more source

An Immediate‐Response Detection System for γ‐Hydroxybutyrate to Enhance Personal Safety in Social Environments

Advanced Science, EarlyView.
A graphene‐based electrical biosensor enables rapid and highly sensitive detection of GHB at 100 fm in both standard solutions and artificial urine, providing reliable point‐of‐need screening for drug‐facilitated sexual assault. The platform demonstrates strong selectivity, fast response, and a wide dynamic range, supporting accurate detection in ...
Jai Eun An, Jisung Kwak, Kyung Ho Kim, Chaeeun Kim, Sung Eun Seo, Nathaniel S. Hwang, Yong‐Sang Ryu, Hyun Seok Song, Oh Seok Kwon   +8 more
wiley   +1 more source

An Efficient Detection Platform Based on Mesoporous Au@Cr2O3 Particles with Schwarz P Surface for Precise Periodontitis Metabolite Profiling

Advanced Science, EarlyView.
A non‐invasive periodontitis diagnosis platform was developed using Au nanoparticles‐decorated mesoporous Cr2O3 (Au@mCr2O3) particles with Schwarz P surface as matrix for saliva metabolic fingerprinting (SMFs) analysis via MALDI‐MS. With the assistance of machine learning of SMFs, this platform enables efficient diagnosis and the screening of potential
Yue Sun, Yan Wang, Fangying Shi, Wenhe Xie, Yiding Zhang, Heyuhan Zhang, Chunhui Deng, Limin Wu, Meihua Chen, Yonghui Deng   +9 more
wiley   +1 more source

High-resolution proteomics unveils salivary gland disruption and saliva-hemolymph protein exchange in Plasmodium-infected mosquitoes

Nature Communications
Plasmodium sporozoites, the infective stage of malaria, must invade the mosquito salivary glands (SGs) before being transmitted to a vertebrate host. However, the physiological and biochemical effects of this invasion remain largely unexplored.
Thiago Luiz Alves e Silva, Sachi Kanatani, Ana Beatriz Barletta Ferreira, Cindi L. Schwartz, Benjamin Liffner, Octavio A. C. Talyuli, Janet Olivas, Bianca M. Nagata, Zarna Rajeshkumar Pala, Tales Pascini, Derron A. Alves, Ming Zhao, Motoshi Suzuki, Lilian P. Dorner, Friedrich Frischknecht, Isabelle Coppens, Carolina Barillas-Mury, Sabrina Absalon, Jose M. C. Ribeiro, Photini Sinnis, Joel Vega-Rodriguez   +20 more
doaj   +1 more source

Sergentomyia schwetzi: Salivary gland transcriptome, proteome and enzymatic activities in two lineages adapted to different blood sources.

PLoS ONE, 2020
During the blood feeding, sand fly females inject saliva containing immunomodulatory and anti-haemostatic molecules into their vertebrate hosts. The saliva composition is species-specific, likely due to an adaptation to particular haemostatic pathways of
Nikola Polanska, Aygul Ishemgulova, Vera Volfova, Pavel Flegontov, Jan Votypka, Vyacheslav Yurchenko, Petr Volf   +6 more
doaj   +1 more source

Towards a Proteomic Catalogue and Differential Annotation of Salivary Gland Proteins in Blood Fed Malaria Vector Anopheles culicifacies by Mass Spectrometry. [PDF]

PLoS ONE, 2016
In order to understand the importance of functional proteins in mosquito behavior, following blood meal, a baseline proteomic dataset is essential for providing insights into the physiology of blood feeding.
Ritu Rawal, Sonam Vijay, Kavita Kadian, Jagbir Singh, Veena Pande, Arun Sharma   +5 more
doaj   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

Salivary gland transcriptomes and proteomes of Phlebotomus tobbi and Phlebotomus sergenti, vectors of leishmaniasis.

PLoS Neglected Tropical Diseases, 2012
BackgroundPhlebotomus tobbi is a vector of Leishmania infantum, and P. sergenti is a vector of Leishmania tropica. Le. infantum and Le. tropica typically cause visceral or cutaneous leishmaniasis, respectively, but Le.
Iva Rohoušová, Sreenath Subrahmanyam, Věra Volfová, Jianbing Mu, Petr Volf, Jesus G Valenzuela, Ryan C Jochim   +6 more
doaj   +1 more source